L-2-AMINOBUTYRIC-3,3-D2 ACID

Base Information

• Chemical Name: L-2-AMINOBUTYRIC-3,3-D2 ACID
• CAS No.: 352431-37-9
• Molecular Formula: C₄H₉NO₂
• Molecular Weight: 106.094
• Mol file: 352431-37-9.mol

Synonyms:L-2-AMINOBUTYRIC-3,3-D2 ACID

Chemical Property of L-2-AMINOBUTYRIC-3,3-D2 ACID

Chemical Property:

• PSA: 63.32000
• LogP: 0.50860

Purity/Quality:

L-2-Aminobutyric-3,3-d2Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: L-2-Aminobutyric-3,3-d2 Acid (CAS# 352431-37-9) is a useful isotopically labeled research compound.

Technology Process of L-2-AMINOBUTYRIC-3,3-D2 ACID

There total 2 articles about L-2-AMINOBUTYRIC-3,3-D2 ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

3-Phenyl-5-<1'-13C,1'-D2>ethylhydantoin (73377-67-0) → (R,S)-2-Amino<3-13C,3-D2>butyric Acid (73377-68-1,352431-37-9)

Guidance literature:

With barium dihydroxide; In water; at 150 - 160 ℃; for 1h;

DOI:10.1021/jo01299a035

Reference yield:

C11H14(2)H5NO5 (1246820-39-2) → (+/-)-(3,4-(2)H5)-2-Aminobutanoic acid (1219373-19-9,352431-37-9)

Guidance literature:

With hydrogenchloride; for 4h; Heating;

DOI:10.1039/a605623g

Reference yield:

(R,S)-2-Amino<3-13C,3-D2>butyric Acid (73377-68-1,352431-37-9) → C33(13)CH35(2)H2N5O5

Guidance literature:

for 96h; Yield given; Claviceps purpurea strain PCCE₁;

DOI:10.1021/jo01299a035

upstream raw materials:

3-Phenyl-5-<1'-13C,1'-D2>ethylhydantoin

C₁₁H₁₄⁽²⁾H₅NO₅

Refernces

• 1、 Belzecki, Czeslaw M.,Quigley, Francoise R.,Floss, Heinz G.,Crespi-Perellino, Nicoletta,Guicciardi, Augusto. "Mechanism of α-Hydroxy-α-Amino Acid Formation in the Biosynthesis of Peptide Ergot Alkaloids". . p. 2215 - 2217. Retrieved 2007/10/02.