2-Amino-5-anilino-5-oxopentanoic acid

Base Information

• Chemical Name: 2-Amino-5-anilino-5-oxopentanoic acid
• CAS No.: 4337-38-6
• Molecular Formula: C₁₁H₁₄N₂O₃
• Molecular Weight: 222.244
• ChEMBL ID: CHEMBL4077941
• DSSTox Substance ID: DTXSID60407339
• Mol file: 4337-38-6.mol

Synonyms:4337-38-6;DL-Glutamic acid gamma-anilide;2-amino-5-anilino-5-oxopentanoic acid;2-Amino-5-oxo-5-(phenylamino)pentanoic acid;2-amino-4-(phenylcarbamoyl)butanoic Acid;H-Gln(Ph)-OH;DL-2-Amino-5-anilide-5-oxopentanoic acid;H-DL-Glu(anilide)-OH;SCHEMBL2522620;CHEMBL4077941;DTXSID60407339;STR07157;AKOS027327989;FT-0635237;FT-0774262

Chemical Property of 2-Amino-5-anilino-5-oxopentanoic acid

Chemical Property:

• PSA: 95.91000
• LogP: 2.16700
• Storage Temp.: −20°C
• XLogP3: -2.1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 222.10044231
• Heavy Atom Count: 16
• Complexity: 250

Purity/Quality:

98%Min ^*data from raw suppliers

2-Amino-5-oxo-5-(phenylamino)pentanoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NC(=O)CCC(C(=O)O)N

Technology Process of 2-Amino-5-anilino-5-oxopentanoic acid

There total 4 articles about 2-Amino-5-anilino-5-oxopentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N5-phenyl-DL-glutamine (4337-38-6)

Guidance literature:

With hydrazine hydrate;

DOI:10.1021/ja01523a064

Reference yield:

N5-phenyl-N2,N2-phthaloyl-glutamine (52604-91-8) → N5-phenyl-DL-glutamine (4337-38-6)

Guidance literature:

With hydrazine; In ethanol;

DOI:10.1515/bchm2.1960.322.1.101

Reference yield:

6-oxo-1-phenyl-1,4,5,6-tetrahydro-pyridazine-3-carboxylic acid (33548-33-3) → N5-phenyl-DL-glutamine (4337-38-6)

Guidance literature:

With palladium on activated charcoal; water; Hydrogenation;

upstream raw materials:

6-oxo-1-phenyl-1,4,5,6-tetrahydro-pyridazine-3-carboxylic acid

N⁵-phenyl-N²,N²-phthaloyl-glutamine

Refernces