CHOLESTEROL-3-13C

Base Information

• Chemical Name: CHOLESTEROL-3-13C
• CAS No.: 334974-05-9
• Molecular Formula: C₂₇H₄₆O
• Molecular Weight: 388.64
• Mol file: 334974-05-9.mol

Synonyms:CHOLESTEROL-3-13C

Chemical Property of CHOLESTEROL-3-13C

Chemical Property:

• PSA: 20.23000
• LogP: 7.38870

Purity/Quality:

99% ^*data from raw suppliers

Cholesterol-3-13C ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CHOLESTEROL-3-13C

There total 6 articles about CHOLESTEROL-3-13C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

C28(13)C2H52OSi (82938-10-1) → <3,4-13C2>-4-Cholesten-3β-ol + <3,4-13C2>-5-Cholesten-3α-ol (78887-48-6,334974-05-9) + cholesterol-(13)C4,(13)C3 (78887-48-6,334974-05-9)

Guidance literature:

With sodium tetrahydroborate; In diethyl ether; isopropyl alcohol; for 4h; Yields of byproduct given; Ambient temperature;

DOI:10.1016/0039-128X(82)90147-7

Reference yield: 50.0%

C28(13)C2H52OSi (82938-10-1) → <3,4-13C2>-4-Cholesten-3β-ol + <3,4-13C2>-5-Cholesten-3α-ol (78887-48-6,334974-05-9) + cholesterol-(13)C4,(13)C3 (78887-48-6,334974-05-9)

Guidance literature:

With sodium tetrahydroborate; In diethyl ether; isopropyl alcohol; for 4h; Yields of byproduct given; Ambient temperature;

DOI:10.1016/0039-128X(82)90147-7

Reference yield:

<3,4-13C2>-4-Cholesten-3-one (82938-09-8) → <3,4-13C2>-5-Cholesten-3α-ol (78887-48-6,334974-05-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / (Me₃Si)2NH / pyridine / 4 h / Ambient temperature

2: NaBH₄ / diethyl ether; propan-2-ol / 4 h / Ambient temperature

With sodium tetrahydroborate; 1,1,1,3,3,3-hexamethyl-disilazane; In pyridine; diethyl ether; isopropyl alcohol;

DOI:10.1016/0039-128X(82)90147-7

upstream raw materials:

C₂₈⁽¹³⁾C₂H₅₂OSi

<3,4-13C2>-4-Cholesten-3-one

Refernces