CIS,CIS,CIS-TETRAKIS(DIPHENYLPHOSPHINOMETHYL)CYCLOPENTANE

Base Information

• Chemical Name: CIS,CIS,CIS-TETRAKIS(DIPHENYLPHOSPHINOMETHYL)CYCLOPENTANE
• CAS No.: 333380-86-2
• Molecular Formula: C57H54 P4
• Molecular Weight: 806.83
• Hs Code.: 2902909090
• Mol file: 333380-86-2.mol

Synonyms:Phosphine,[(1R,2R,3S,4S)-1,2,3,4-cyclopentanetetrayltetrakis(methylene)]tetrakis[diphenyl-,rel- (9CI); Tedicyp;all-cis-1,2,3,4-Tetrakis[(diphenylphosphino)methyl]cyclopentane;cis,cis,cis-1,2,3,4-Tetrakis[(diphenylphosphino)methyl]cyclopentane;rel-[(1R,2R,3S,4S)-1,2,3,4-Cyclopentanetetrayltetrakis(methylene)]tetrakis[diphenylphosphine]

Chemical Property of CIS,CIS,CIS-TETRAKIS(DIPHENYLPHOSPHINOMETHYL)CYCLOPENTANE

Chemical Property:

• Melting Point: 79℃
• PSA: 54.36000
• LogP: 10.39610

Purity/Quality:

98%,99%, ^*data from raw suppliers

CIS,CIS,CIS-TETRAKIS(DIPHENYLPHOSPHINOMETHYL)CYCLOPENTANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CIS,CIS,CIS-TETRAKIS(DIPHENYLPHOSPHINOMETHYL)CYCLOPENTANE

There total 4 articles about CIS,CIS,CIS-TETRAKIS(DIPHENYLPHOSPHINOMETHYL)CYCLOPENTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(1RS,2RS,3SR,4SR)-1,2,3,4-tetrakis((boranatodiphenylphosphanyl)methyl)cyclopentane → (1RS,2RS,3SR,4SR)-1,2,3,4-tetrakis((diphenylphosphanyl)methyl)cyclopentane (333380-86-2)

Guidance literature:

With diethylamine; at 55 - 60 ℃; for 10h;

DOI:10.1021/jo001146j

Reference yield:

chloro-diphenylphosphine (1079-66-9,74391-44-9) + (1RS,2RS,3SR,4SR)-1,2,3,4-tetrakis(((tolyl-4-sylfonyl)oxy)methyl)cyclopentane (62349-01-3) → (1RS,2RS,3SR,4SR)-1,2,3,4-tetrakis((diphenylphosphanyl)methyl)cyclopentane (333380-86-2)

Guidance literature:

chloro-diphenylphosphine; With lithium; In tetrahydrofuran; at 20 ℃; for 3h;

(1RS,2RS,3SR,4SR)-1,2,3,4-tetrakis(((tolyl-4-sylfonyl)oxy)methyl)cyclopentane; In tetrahydrofuran; at 20 ℃; for 5h; Further stages.;

DOI:10.1021/jo001146j

Reference yield:

(1RS,2RS,3SR,4SR)-1,2,3,4-tetrakis(hydroxymethyl)cyclopentane (150617-83-7) → (1RS,2RS,3SR,4SR)-1,2,3,4-tetrakis((diphenylphosphanyl)methyl)cyclopentane (333380-86-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 65 percent / pyridine / 5 h / -20 °C

2.1: Li / tetrahydrofuran / 3 h / 20 °C

2.2: tetrahydrofuran / 5 h / 20 °C

With pyridine; lithium; In tetrahydrofuran;

DOI:10.1021/jo001146j

upstream raw materials:

chloro-diphenylphosphine

(1RS,2RS,3SR,4SR)-1,2,3,4-tetrakis(((tolyl-4-sylfonyl)oxy)methyl)cyclopentane

(1RS,2RS,3SR,4SR)-1,2,3,4-tetrakis(hydroxymethyl)cyclopentane

(1RS,7SR,8SR,10RS)-8,10-bis(hydroxymethyl)-4,4-dimethyl-3,5-dioxabicyclo[5.3.0]decane

Refernces