AC-LYS (AC)-OH

Base Information

• Chemical Name: AC-LYS (AC)-OH
• CAS No.: 499-86-5
• Molecular Formula: C₁₀H₁₈N₂O₄
• Molecular Weight: 230.264
• Hs Code.: 2924190090
• Mol file: 499-86-5.mol

Synonyms:a,e-Diacetyl-L-lysine;Lysine,N2,N6-diacetyl-, L- (6CI,7CI,8CI);Diacetyl-L-lysine;Na,Ne-Diacetyl-L-lysine;

Chemical Property of AC-LYS (AC)-OH

Chemical Property:

• Boiling Point: 578.5 °C at 760 mmHg
• PKA: 3.65±0.10(Predicted)
• Flash Point: 303.7 °C
• PSA: 95.50000
• Density: 1.148 g/cm³
• LogP: 0.66390
• Storage Temp.: -15°C
• Solubility.: Methanol (Slightly), Water (Slightly, Sonicated)

Purity/Quality:

99% ^*data from raw suppliers

Ac-lys(ac)-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Ac-lys(ac)-oh was used in the reaction of HOCl with amino acids and peptides with ESR evidence for rapid rearrangement and fragmentation reactions of nitrogen-centered radicals.

Technology Process of AC-LYS (AC)-OH

There total 2 articles about AC-LYS (AC)-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

lysine acetylsalicylate (357657-22-8,37933-78-1,77337-52-1) → L-lysine (56-87-1,3506-25-0) + H-Lys(acetyl)-OH (692-04-6) + N-Ac-L-Lys-OH (1946-82-3,152473-69-3) + Nα,Nε-diacetyl-L-lysine (35436-74-9,499-86-5) + salicylic acid (69-72-7,25496-36-0,8052-31-1) + aspirin (50-78-2,98201-60-6)

Guidance literature:

In water; at 23 ℃; Rate constant; pH 2.0 - 10.0;

DOI:10.1002/ardp.19853180205

Reference yield:

L-lysine (56-87-1,3506-25-0) + aspirin (50-78-2,98201-60-6) → H-Lys(acetyl)-OH (692-04-6) + N-Ac-L-Lys-OH (1946-82-3,152473-69-3) + lysine acetylsalicylate (357657-22-8,37933-78-1,77337-52-1) + Nα,Nε-diacetyl-L-lysine (35436-74-9,499-86-5) + salicylic acid (69-72-7,25496-36-0,8052-31-1)

Guidance literature:

In water; at 23 ℃; Rate constant; Product distribution; pH 2.0 - 10.0;

DOI:10.1002/ardp.19853180205

Reference yield: 82.0%

4-aminobenzenemethanol (623-04-1) + Nα,Nε-diacetyl-L-lysine (35436-74-9,499-86-5) → para-hydroxymethylphenylamine Nα,Nε-diacetyl-L-lysine amide

Guidance literature:

N^α,N^ε-diacetyl-L-lysine; With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

4-aminobenzenemethanol; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1039/d0ob00333f

upstream raw materials:

lysine acetylsalicylate

L-lysine

aspirin

Downstream raw materials:

diacetyllysine S-α-phenylethylamide

(S)-2,6-Bis-acetylamino-hexanoic acid 2-nitro-phenyl ester

(R)-2-[2-((S)-2,6-Bis-acetylamino-hexanoylamino)-ethanesulfonylamino]-propionic acid benzyl ester

Refernces