3-fluoroanisole

Base Information

• Chemical Name: 3-fluoroanisole
• CAS No.: 456-99-5
• Molecular Formula: C14H11 F O3
• Molecular Weight: 246.238
• Mol file: 456-99-5.mol

Synonyms:3-FLUOROANISOLE

Chemical Property of 3-fluoroanisole

Chemical Property:

• PSA: 35.53000
• LogP: 3.43910

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-fluoroanisole

There total 1 articles about 3-fluoroanisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

→ 2-fluoro-4-(4-methoxy-phenoxy)-benzaldehyde (456-99-5)

Guidance literature:

Reference yield:

2-fluoro-4-(4-methoxy-phenoxy)-benzaldehyde (456-99-5) → C14H12FNO3

Guidance literature:

With hydroxylamine; In water; N,N-dimethyl-formamide; at 20 - 100 ℃;

Reference yield:

2-fluoro-4-(4-methoxy-phenoxy)-benzaldehyde (456-99-5) → 2-fluoro-4-(4-methoxy-phenoxy)-benzylamine (1126632-69-6)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine / N,N-dimethyl-formamide; water / 20 - 100 °C

2: hydrogen; ammonia / Raney nickel / methanol / 4 h / 20 °C / 2250.23 Torr

With ammonia; hydrogen; hydroxylamine; Raney nickel; In methanol; water; N,N-dimethyl-formamide;

Downstream raw materials:

2-fluoro-4-(4-methoxy-phenoxy)-benzylamine

Refernces