Technology Process of methyl 2,2-diphenyl-4-pentenoate
There total 5 articles about methyl 2,2-diphenyl-4-pentenoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
methyl 2,2-diphenylacetate;
With
n-butyllithium; diisopropylamine;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.5h;
Inert atmosphere;
allyl bromide;
With
tetra-(n-butyl)ammonium iodide;
In
tetrahydrofuran;
at -78 - 20 ℃;
for 16h;
Inert atmosphere;
DOI:10.1002/anie.201500596
- Guidance literature:
-
methyl 2,2-diphenylacetate;
With
lithium diisopropyl amide;
In
tetrahydrofuran;
at -78 ℃;
for 0.166667h;
Inert atmosphere;
3-chloroprop-1-ene;
In
tetrahydrofuran;
at -78 - 20 ℃;
for 25h;
Inert atmosphere;
DOI:10.1039/c0ob00701c
- Guidance literature:
-
tetrakis(triphenylphosphine) palladium(0);
In
N,N-dimethyl-formamide;
at 0 ℃;
for 0.5h;
Product distribution;
Mechanism;
var. solvent, var. ketenes;
DOI:10.1021/jo00385a009
