1-phenyl-2-decanone

Base Information

• Chemical Name: 1-phenyl-2-decanone
• CAS No.: 32508-91-1
• Molecular Formula: C₁₆H₂₄O
• Molecular Weight: 232.366
• Mol file: 32508-91-1.mol

Synonyms:1-phenyl-2-decanone

Chemical Property of 1-phenyl-2-decanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-phenyl-2-decanone

There total 19 articles about 1-phenyl-2-decanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-Phenylacetyl-nonanoic acid methyl ester (83698-31-1) → 1-phenyl-2-decanone (32508-91-1)

Guidance literature:

With sodium hydroxide; In methanol; water; Heating;

Reference yield: 73.0%

triphenylborane (960-71-4) + (Z)-(2-acetoxy-1-decenyl)(phenyl)iodonium bromide → 1-phenyl-2-decanone (32508-91-1)

Guidance literature:

(Z)-(2-acetoxy-1-decenyl)(phenyl)iodonium bromide; With lithium ethoxide; In tetrahydrofuran; at -78 ℃;

triphenylborane; In tetrahydrofuran; at -78 - 20 ℃; for 1.5h;

DOI:10.1021/ol0495669

Reference yield: 67.0%

triphenylborane (960-71-4) + (Z)-β-acetoxyvinyl(phenyl)(tetrafluoroborato)-λ3-iodane → 1-phenyl-2-decanone (32508-91-1)

Guidance literature:

(Z)-β-acetoxyvinyl(phenyl)(tetrafluoroborato)-λ³-iodane; With lithium ethoxide; In tetrahydrofuran; at -78 ℃;

triphenylborane; In tetrahydrofuran; at -78 - 20 ℃; for 1.5h;

DOI:10.1021/ol0495669

upstream raw materials:

Nonanoyl chloride

benzyl bromide

oct-1-ene

carbon monoxide

Downstream raw materials:

1-[4-(1,1-dimethylethyl)phenyl]-2-phenylethanone

S-methyl nonanethioate

octyl p-cyanophenylmethyl ketone

1-(4-chlorophenyl)-2-decanone

Refernces

• 1、 Arisawa, Mieko,Kuwajima, Manabu,Toriyama, Fumihiko,Li, Guangzhe,Yamaguchi, Masahiko. "Rhodium-catalyzed acyl-transfer reaction between benzyl ketones and thioesters: Synthesis of unsymmetric ketones by ketone CO-C bond cleavage and intermolecular rearrangement". supporting information; experimental part. p. 3804 - 3807. Retrieved 2012/09/07.
• 2、 Ochiai, Masahito,Tuchimoto, Yoshimi,Higashiura, Nobuyuki. "Reaction of unstabilized iodonium ylides with organoboranes". . p. 1505 - 1508. Retrieved 2007/10/03.