4-Hexenoic acid, 2-acetyl-2,3-dimethyl-, ethyl ester, (E)- (stereoisom er 2)

Base Information

• Chemical Name: 4-Hexenoic acid, 2-acetyl-2,3-dimethyl-, ethyl ester, (E)- (stereoisom er 2)
• CAS No.: 24810-56-8
• Molecular Formula: C₁₂H₂₀O₃
• Molecular Weight: 212.289
• Mol file: 24810-56-8.mol

Synonyms:4-Hexenoic acid, 2-acetyl-2,3-dimethyl-, ethyl ester, (E)- (stereoisom er 2)

Chemical Property of 4-Hexenoic acid, 2-acetyl-2,3-dimethyl-, ethyl ester, (E)- (stereoisom er 2)

Chemical Property:

• Boiling Point: 97 - 100 °C (3 mmHg)
• PSA: 43.37000
• LogP: 2.35700

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Hexenoic acid, 2-acetyl-2,3-dimethyl-, ethyl ester, (E)- (stereoisom er 2)

There total 2 articles about 4-Hexenoic acid, 2-acetyl-2,3-dimethyl-, ethyl ester, (E)- (stereoisom er 2) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

2-acetylpropanoic acid ethyl ester (609-14-3) + penta-1,3-diene (504-60-9,17410-45-6,25212-15-1,64940-84-7) → (E)-2-Acetyl-2-methyl-hept-4-enoic acid ethyl ester + (E)-2-Acetyl-2,3-dimethyl-hex-4-enoic acid ethyl ester (24810-56-8)

Guidance literature:

[Pd(1,2-bis(diisopropylphosphino)ethane)]n; In tetrahydrofuran; at 60 ℃; for 60h;

DOI:10.1055/s-1990-27010

Reference yield:

→ (E)-2-Acetyl-2,3-dimethyl-hex-4-enoic acid ethyl ester (24810-56-8)

Guidance literature:

2-Methylacetoacetat, NaH, 4-Bromo-2-penten;

upstream raw materials:

2-acetylpropanoic acid ethyl ester

penta-1,3-diene

Refernces