3,4-dimethylphenyl phenyl ether

Base Information

• Chemical Name: 3,4-dimethylphenyl phenyl ether
• CAS No.: 52509-74-7
• Molecular Formula: C₁₄H₁₄O
• Molecular Weight: 198.265
• Mol file: 52509-74-7.mol

Synonyms:3,4-dimethylphenyl phenyl ether

Chemical Property of 3,4-dimethylphenyl phenyl ether

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3,4-dimethylphenyl phenyl ether

There total 5 articles about 3,4-dimethylphenyl phenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3,4-Dimethylphenol (95-65-8) + chlorobenzene (108-90-7) → 3,4-dimethylphenyl phenyl ether (52509-74-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 12h;

DOI:10.1002/adsc.201000977

Reference yield: 97.0%

3,4-Dimethylphenol (95-65-8) + iodobenzene (591-50-4) → 3,4-dimethylphenyl phenyl ether (52509-74-7)

Guidance literature:

With copper(II) glycinate monohydrate; potassium hydroxide; In dimethyl sulfoxide; at 80 ℃; for 8h;

DOI:10.1016/j.tetlet.2012.06.071

Reference yield: 94.0%

3,4-Dimethylphenol (95-65-8) + bromobenzene (108-86-1,52753-63-6) → 3,4-dimethylphenyl phenyl ether (52509-74-7)

Guidance literature:

With copper(II) glycinate monohydrate; potassium hydroxide; In dimethyl sulfoxide; at 80 ℃; for 8h;

DOI:10.1016/j.tetlet.2012.06.071

upstream raw materials:

3,4-Dimethylphenol

bromobenzene

potassium phenolate

iodobenzene

Downstream raw materials:

4-phenoxyphthalic acid

Refernces

• 1、 Ghatak, Avishek,Khan, Sagar,Roy, Rimi,Bhar, Sanjay. "Chemoselective and ligand-free synthesis of diaryl ethers in aqueous medium using recyclable alumina-supported nickel nanoparticles". supporting information. p. 7082 - 7088. Retrieved 2015/02/02.
• 2、 Yang, Li,Yang, Qichao,Shi, Jianxin,Wang, Yufang,Zhang, Mingjie. "Betti base as an efficient ligand for copper-catalyzed ullmann coupling of phenol with aryl halides". supporting information. p. 2468 - 2477. Retrieved 2014/08/05.