1-VINYL-1,2,4-TRIAZOLE

Base Information

• Chemical Name: 1-VINYL-1,2,4-TRIAZOLE
• CAS No.: 2764-83-2
• Molecular Formula: C4H5 N3
• Molecular Weight: 95.1038
• Hs Code.: 2933990090
• Mol file: 2764-83-2.mol

Synonyms:1H-1,2,4-Triazole,1-vinyl- (7CI,8CI); 1-Vinyl-1,2,4-triazole; N-Vinyl-1,2,4-Triazole

Chemical Property of 1-VINYL-1,2,4-TRIAZOLE

Chemical Property:

• Vapor Pressure: 0.601mmHg at 25°C
• Refractive Index: n20/D 1.511
• Boiling Point: 188.4°C at 760 mmHg
• PKA: 2.33±0.10(Predicted)
• Flash Point: 67.7°C
• PSA: 30.71000
• Density: 1.099 g/mL at 20 °C(lit.)
• LogP: 0.37860

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Vinyl-1,2,4-triazole ≥97.0% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-Vinyl-1,2,4-triazole is mainly used in the preparation of poly(1-vinyl-1,2,4-triazole) and its copolymers.Introduction of 1-vinyl-1,2,4-triazole in polysaccharide based semi-degradable hydrogel to increase the equilibrium water content and endow hydrogels with anti-bacterial and anti-inflammatory abilities has also been reported.

Technology Process of 1-VINYL-1,2,4-TRIAZOLE

There total 14 articles about 1-VINYL-1,2,4-TRIAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1,2,4-Triazole (288-88-0) + vinyl acetate (108-05-4,9003-20-7) → 1-vinyl-1H-1,2,4-triazole (2764-83-2)

Guidance literature:

With mercury(II) diacetate; hydroquinone; trifluoroacetic acid; at 70 ℃; for 3h;

DOI:10.1023/A:1020874201056

Reference yield: 78.0%

1,2,4-Triazole (288-88-0) + acetylene (74-86-2,25067-58-7) → 1-vinyl-1H-1,2,4-triazole (2764-83-2)

Guidance literature:

With potassium hydroxide; In 1,4-dioxane; at 210 - 220 ℃; for 4h; under 10640.7 Torr;

DOI:10.1016/j.jorganchem.2020.121352

Reference yield: 70.0%

1-(2-chloroethyl)-1H-1,2,4-triazole (3236-66-6) → 1-vinyl-1H-1,2,4-triazole (2764-83-2)

Guidance literature:

With 4-methylmorpholine N-oxide; potassium hydroxide; In water; at 20 - 25 ℃; for 5h;

DOI:10.1134/S1070363216020377

upstream raw materials:

1,2,4-Triazole

vinyl acetate

1,2-dichloro-ethane

ethylene dibromide

Downstream raw materials:

1-ethyl-1H-1,2,4-triazole

Refernces

• 1、 Hopff,Lippay. "-". . p. 157,160. Retrieved 1963.
• 2、 Lebedeva,Kalaus. "Formation of N-vinyl derivatives of 1,2,4-triazole". . p. 714 - 714. Retrieved 1989.
• 3、 Sitte, Nikolai A.,Menche, Maximilian,Tu?ina, Pavel,Bienewald, Frank,Sch?fer, Ansgar,Comba, Peter,Rominger, Frank,Hashmi, A. Stephen K.,Schaub, Thomas. "Phosphine-Catalyzed Vinylation at Low Acetylene Pressure". . p. 13041 - 13055. Retrieved 2021/09/18.