1-(3-methylphenyl)-2-phenyl-1,2-ethanedione

Base Information

• Chemical Name: 1-(3-methylphenyl)-2-phenyl-1,2-ethanedione
• CAS No.: 40103-79-5
• Molecular Formula: C₁₅H₁₂O₂
• Molecular Weight: 224.259
• Mol file: 40103-79-5.mol

Synonyms:1-(3-methylphenyl)-2-phenyl-1,2-ethanedione

Chemical Property of 1-(3-methylphenyl)-2-phenyl-1,2-ethanedione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3-methylphenyl)-2-phenyl-1,2-ethanedione

There total 20 articles about 1-(3-methylphenyl)-2-phenyl-1,2-ethanedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

meta-bromotoluene (591-17-3) + 1-phenyl-2-hydroxyethanone (582-24-1) → 1-(3-methylphenyl)-2-phenyl-1,2-ethanedione (40103-79-5)

Guidance literature:

1-phenyl-2-hydroxyethanone; With potassium phosphate; bis(η3-allyl-μ-chloropalladium(II)); XPhos; In tert-butyl alcohol; at 20 ℃; for 0.5h; Schlenk technique; Inert atmosphere; Sealed tube;

meta-bromotoluene; In tert-butyl alcohol; at 100 ℃; for 18h; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1039/d0ob00575d

Reference yield: 97.0%

(E)-3-methylstilbene (14064-48-3) → 1-(3-methylphenyl)-2-phenyl-1,2-ethanedione (40103-79-5)

Guidance literature:

With water; iodine; oxygen; In acetonitrile; at 140 ℃; for 20h; chemoselective reaction; Sealed tube;

DOI:10.1039/c3ra41489b

Reference yield: 94.0%

1-methyl-3-(2-phenylethynyl)benzene (14635-91-7) → 1-(3-methylphenyl)-2-phenyl-1,2-ethanedione (40103-79-5)

Guidance literature:

With tert.-butylhydroperoxide; (p-cymene)ruthenium(II) chloride; iodine; In 1,4-dioxane; water; at 80 ℃; for 12h;

DOI:10.1002/adsc.201000250

upstream raw materials:

1-methyl-3-(2-phenylethynyl)benzene

3-methyl-stilbene

methyl 1-phenyl-3-(mtolyl)propane-1,3-dione

N-phenyl benzoyl amide

Downstream raw materials:

C₁₇H₁₇N₃O

Refernces

• 1、 Shen, Duyi,Wang, Hongyan,Zheng, Yanan,Zhu, Xinjing,Gong, Peiwei,Wang, Bin,You, Jinmao,Zhao, Yulei,Chao, Mianran. "Catalyst-Free and Transition-Metal-Free Approach to 1,2-Diketones via Aerobic Alkyne Oxidation". . p. 5354 - 5361. Retrieved 2021/05/05.
• 2、 Fujiwara, Sakiko,Kon, Yoshihiro,Mashima, Kazushi,Nagae, Haruki,Okuda, Jun,Sakamoto, Kazutaka,Sato, Kazuhiko,Schindler, Tobias. "Aerobic oxygenation of α-methylene ketones under visible-light catalysed by a CeNi3complex with a macrocyclic tris(salen)-ligand". . p. 11169 - 11172. Retrieved 2021/11/04.