2-(Dimethylamino)ethyl carbamate

Base Information

• Chemical Name: 2-(Dimethylamino)ethyl carbamate
• CAS No.: 4220-32-0
• Molecular Formula: C5H12 N2 O2
• Molecular Weight: 132.162
• Hs Code.: 2924199090
• European Community (EC) Number: 224-163-4
• NSC Number: 27157
• UNII: Y60Z74U51E
• DSSTox Substance ID: DTXSID70195033
• Nikkaji Number: J205.644E
• Wikidata: Q27294298
• Mol file: 4220-32-0.mol

Synonyms:N-demethylcarbachol;N-demethylcarbachol monohydrochloride

Chemical Property of 2-(Dimethylamino)ethyl carbamate

Chemical Property:

• Vapor Pressure: 0.0578mmHg at 25°C
• Melting Point: 64 °C
• Boiling Point: 232.8°C at 760 mmHg
• PKA: 13.32±0.50(Predicted)
• Flash Point: 94.6°C
• PSA: 55.56000
• Density: 1.053g/cm³
• LogP: 0.34360
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 132.089877630
• Heavy Atom Count: 9
• Complexity: 93

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCOC(=O)N

Technology Process of 2-(Dimethylamino)ethyl carbamate

There total 4 articles about 2-(Dimethylamino)ethyl carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(N,N-dimethylamino)ethanol (108-01-0) + carbamic chloride (463-72-9) → Dimethylaminoethyl carbamate (4220-32-0)

Guidance literature:

In diethyl ether;

DOI:10.1021/jm00283a021

Reference yield:

2-(N,N-dimethylamino)ethanol (108-01-0) + urethane (51-79-6) → Dimethylaminoethyl carbamate (4220-32-0)

Guidance literature:

With aluminum methoxide; In toluene;

Reference yield:

2-chloroethyl carbamate (2114-18-3) + dimethyl amine (124-40-3) → Dimethylaminoethyl carbamate (4220-32-0)

Guidance literature:

at 95 ℃;

upstream raw materials:

2-chloroethyl carbamate

dimethyl amine

2-(N,N-dimethylamino)ethanol

carbamic chloride

Downstream raw materials:

(2-Benzhydryloxy-ethyl)-(2-carbamoyloxy-ethyl)-dimethyl-ammonium; chloride

carbachol iodide

Refernces