5-Iodo-2-methyl-1,3-benzothiazole

Base Information

• Chemical Name: 5-Iodo-2-methyl-1,3-benzothiazole
• CAS No.: 90414-61-2
• Molecular Formula: C₈H₆INS
• Molecular Weight: 275.113
• Hs Code.: 2934208090
• Mol file: 90414-61-2.mol

Synonyms:2-Methyl-5-iodobenzothiazole;5-Iodo-2-methylbenzothiazole

Chemical Property of 5-Iodo-2-methyl-1,3-benzothiazole

Chemical Property:

• PSA: 41.13000
• LogP: 3.20930
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

97% ^*data from raw suppliers

5-Iodo-2-methyl-1,3-benzothiazole 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Iodo-2-methyl-1,3-benzothiazole

There total 3 articles about 5-Iodo-2-methyl-1,3-benzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

2-methyl-5-aminobenzothiazole (13382-43-9) → 5-iodo-2-methylbenzothiazole (90414-61-2)

Guidance literature:

2-methyl-5-aminobenzothiazole; With hydrogenchloride; sodium nitrite; for 0.5h;

With potassium iodide; In water; for 0.166667h; Further stages.;

DOI:10.1016/j.tet.2007.11.004

Reference yield:

2-methyl-benzothiazole-5-diazonium; chloride → 5-iodo-2-methylbenzothiazole (90414-61-2)

Guidance literature:

With potassium iodide; In water; acetone; at 0 ℃; for 0.166667h;

Reference yield:

→ 5-iodo-2-methylbenzothiazole (90414-61-2)

Guidance literature:

5-Amino-2-methylbenzothiazol: 1) NaNO2/HCl (0grad) 2) wss.KI;

upstream raw materials:

2-methyl-5-aminobenzothiazole

Downstream raw materials:

2-methyl-1,3-benzothiazole-5-carbonitrile

2-hydroxymethyl-1,3-benzothiazole-5-carboxylic acid

Refernces

• 1、 Ye, Fei,Wang, Chengpeng,Zhang, Yan,Wang, Jianbo. "Synthesis of Aryldiazoacetates through Palladium(0)-Catalyzed Deacylative Cross-Coupling of Aryl Iodides with Acyldiazoacetates". supporting information. p. 11625 - 11628. Retrieved 2016/02/19.
• 2、 -. "NEW BENZOTHIAZOLECARBOXAMIDES". Page/Page column 19. . Retrieved 2008/06/13.