3-Cinnamyloxy-methoxy-benzol

Base Information

• Chemical Name: 3-Cinnamyloxy-methoxy-benzol
• CAS No.: 4646-99-5
• Molecular Formula: C₁₆H₁₆O₂
• Molecular Weight: 240.302
• Mol file: 4646-99-5.mol

Synonyms:3-Cinnamyloxy-methoxy-benzol

Chemical Property of 3-Cinnamyloxy-methoxy-benzol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Cinnamyloxy-methoxy-benzol

There total 2 articles about 3-Cinnamyloxy-methoxy-benzol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

O-methylresorcine (150-19-6) + 3-bromo-1-phenyl-1-propenyl bromide (4392-24-9) → 3-Cinnamyloxy-methoxy-benzol (4646-99-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 65 ℃;

DOI:10.1016/j.tetlet.2012.06.094

Reference yield:

O-methylresorcine (150-19-6) + cinnamyl chloride (2687-12-9) → 3-Cinnamyloxy-methoxy-benzol (4646-99-5) + 1-methoxy-3-((1-phenylallyl) oxy) benzene (1542455-49-1,512789-30-9)

Guidance literature:

cinnamyl chloride; With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; potassium carbonate; In acetonitrile; at 20 ℃; for 0.333333h; Schlenk technique; Inert atmosphere;

O-methylresorcine; In acetonitrile; at 20 ℃; for 16h; Schlenk technique; Inert atmosphere;

DOI:10.1016/j.tetlet.2013.12.074

Reference yield: 93.0%

3-Cinnamyloxy-methoxy-benzol (4646-99-5) → allylbenzene (300-57-2,57807-91-7)

Guidance literature:

With 6,6'-dimethyl-2,2'-bipyridine; (1,2-dimethoxyethane)dichloronickel(II); bis(pinacol)diborane; lithium tert-butoxide; In N,N-dimethyl acetamide; water; at 30 ℃; for 24h; Inert atmosphere;

DOI:10.3390/molecules25030602

upstream raw materials:

O-methylresorcine

3-bromo-1-phenyl-1-propenyl bromide

cinnamyl chloride

Downstream raw materials:

2-cinnamyl-5-methoxyphenol

4-methoxy-1-(1-phenylallyl)-2-(vinyloxy)benzene

4-phenyl-7-methoxy-4H-chromene

5-methoxy-2-(1-phenylallyl)phenol

Refernces

• 1、 Miller, Bradley J.,Pieterse, Tanya,Marais, Charlene,Bezuidenhoudt, Barend C.B.. "Ring-closing metathesis as a new methodology for the synthesis of monomeric flavonoids and neoflavonoids". scheme or table. p. 4708 - 4710. Retrieved 2012/09/21.