4-Chloro-8-methoxycinnoline

Base Information

• Chemical Name: 4-Chloro-8-methoxycinnoline
• CAS No.: 817209-48-6
• Molecular Formula: C₉H₇ClN₂O
• Molecular Weight: 194.62
• DSSTox Substance ID: DTXSID20590251
• Wikidata: Q82483986
• Mol file: 817209-48-6.mol

Synonyms:4-Chloro-8-methoxycinnoline;817209-48-6;Cinnoline,4-chloro-8-methoxy-;SCHEMBL13313325;DTXSID20590251;AKOS006290030;A916182

Chemical Property of 4-Chloro-8-methoxycinnoline

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.629
• Boiling Point: 341.807 °C at 760 mmHg
• Flash Point: 160.519 °C
• PSA: 35.01000
• Density: 1.333 g/cm³
• LogP: 2.29180
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 194.0246905
• Heavy Atom Count: 13
• Complexity: 179

Purity/Quality:

99% ^*data from raw suppliers

4-Chloro-8-methoxycinnoline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC2=C1N=NC=C2Cl

Technology Process of 4-Chloro-8-methoxycinnoline

There total 2 articles about 4-Chloro-8-methoxycinnoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

8-methoxy-1H-cinnolin-4-one (90417-27-9) → 4-chloro-8-methoxy-cinnoline (817209-48-6)

Guidance literature:

With trichlorophosphate;

Reference yield:

→ 4-chloro-8-methoxy-cinnoline (817209-48-6)

Guidance literature:

Reference yield:

4-chloro-8-methoxy-cinnoline (817209-48-6) → 8-methoxy-4-phenoxy-cinnoline

Guidance literature:

upstream raw materials:

8-methoxy-1H-cinnolin-4-one

Refernces