Technology Process of 2-(5-tert-butyl-2-hydroxybenzamido)-4-phenylbenzoic acid
There total 4 articles about 2-(5-tert-butyl-2-hydroxybenzamido)-4-phenylbenzoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
methyl 2-(2-acetoxy-5-tert-butylbenzamido)-4-phenylbenzoate;
With
water; sodium hydroxide;
In
methanol;
at 20 ℃;
for 15h;
With
hydrogenchloride;
In
water;
pH=3;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: pyridine / dichloromethane / 2 h / 20 °C
2.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 0.42 h / 20 °C
3.1: pyridine / dichloromethane / 1.25 h / 20 °C
4.1: sodium hydroxide; water / methanol / 15 h / 20 °C
4.2: pH 3
With
pyridine; oxalyl dichloride; water; sodium hydroxide;
N,N-dimethyl-formamide;
In
methanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 0.42 h / 20 °C
2.1: pyridine / dichloromethane / 1.25 h / 20 °C
3.1: sodium hydroxide; water / methanol / 15 h / 20 °C
3.2: pH 3
With
pyridine; oxalyl dichloride; water; sodium hydroxide;
N,N-dimethyl-formamide;
In
methanol; dichloromethane;
