6-CHLORO-3,4-DIMETHYL-PYRIDAZINE

Base Information

• Chemical Name: 6-CHLORO-3,4-DIMETHYL-PYRIDAZINE
• CAS No.: 873397-60-5
• Molecular Formula: C₆H₇ClN₂
• Molecular Weight: 142.588
• Hs Code.: 2933990090
• Mol file: 873397-60-5.mol

Synonyms:6-CHLORO-3,4-DIMETHYL-PYRIDAZINE

Chemical Property of 6-CHLORO-3,4-DIMETHYL-PYRIDAZINE

Chemical Property:

• PSA: 25.78000
• LogP: 1.74680

Purity/Quality:

98%min ^*data from raw suppliers

6-Chloro-3,4-dimethylpyridazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-CHLORO-3,4-DIMETHYL-PYRIDAZINE

There total 3 articles about 6-CHLORO-3,4-DIMETHYL-PYRIDAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5,6-dimethyl-2H-pyridazin-3-one (100114-19-0) → 6-Chlor-3,4-dimethyl-pyridazin (873397-60-5)

Guidance literature:

With trichlorophosphate;

DOI:10.1002/hlca.19540370514 DOI:10.1021/jo01124a003

Reference yield:

5,6-dimethyl-3-oxo-2,3-dihydropyridazine-4-carbonitrile (40380-36-7) → 6-Chlor-3,4-dimethyl-pyridazin (873397-60-5)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous H₂SO₄ / 150 °C

2: 220 °C

3: POCl₃

With sulfuric acid; trichlorophosphate;

DOI:10.1002/hlca.19540370514

Reference yield:

5,6-dimethyl-3-oxo-2,3-dihydro-pyridazine-4-carboxylic acid (101861-29-4) → 6-Chlor-3,4-dimethyl-pyridazin (873397-60-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 220 °C

2: POCl₃

With trichlorophosphate;

DOI:10.1002/hlca.19540370514

upstream raw materials:

5,6-dimethyl-2H-pyridazin-3-one

5,6-dimethyl-3-oxo-2,3-dihydropyridazine-4-carbonitrile

5,6-dimethyl-3-oxo-2,3-dihydro-pyridazine-4-carboxylic acid