1-Naphthalenecarbonyl chloride, 4-methyl- (9CI)

Base Information

• Chemical Name: 1-Naphthalenecarbonyl chloride, 4-methyl- (9CI)
• CAS No.: 87700-67-2
• Molecular Formula: C12H9 Cl O
• Molecular Weight: 204.656
• Hs Code.: 2916399090
• Mol file: 87700-67-2.mol

Synonyms:4-Methyl-1-naphthalenecarbonylchloride; 4-Methyl-1-naphthoyl chloride

Chemical Property of 1-Naphthalenecarbonyl chloride, 4-methyl- (9CI)

Chemical Property:

• Melting Point: 47-48℃
• Boiling Point: 335℃
• Flash Point: 157℃
• PSA: 17.07000
• Density: 1.231
• LogP: 3.52720

Purity/Quality:

99%, ^*data from raw suppliers

4-Methyl-1-naphthalenecarbonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Naphthalenecarbonyl chloride, 4-methyl- (9CI)

There total 1 articles about 1-Naphthalenecarbonyl chloride, 4-methyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Methyl-1-naphthoic acid (4488-40-8) → 4-methyl-1-naphthalenecarbonyl chloride (87700-67-2)

Guidance literature:

With thionyl chloride;

DOI:10.1039/jr9310000489

Reference yield: 92.0%

3-amino-N-(cyclohexylmethyl)pyridine-2-carboxamide (870762-11-1) + 4-methyl-1-naphthalenecarbonyl chloride (87700-67-2) → N-(cyclohexylmethyl)-3-[(4-methyl-1-naphthalenylcarbonyl)amino]-2-pyridinecarboxamide

Guidance literature:

With dmap; In dichloromethane; at 0 - 20 ℃;

Reference yield: 87.0%

4-methyl-1-naphthalenecarbonyl chloride (87700-67-2) + diphenylphosphane (829-85-6) → (diphenylphosphanyl)(4-methylnaphthalen-1-yl)methanone

Guidance literature:

With triethylamine; In diethyl ether; at 20 ℃;

DOI:10.1021/acs.orglett.7b00579

upstream raw materials:

4-Methyl-1-naphthoic acid

Downstream raw materials:

3-(4-methylnaphthalene-1-carbonyl)-1-[2-(morpholin-4-yl)ethyl]-1H-indole

N-[(4-methylnaphthyl)carbonyl]naphthyl-N-benzylcarboxamide

methyl 4-methyl-1-naphthalenecarboxylate

JWH-149

Refernces

• 1、 Gao, Zeng,Hang, Xiao-Chun,Jiang, Gaoxi,Qian, Jinlong,Yang, Huameng,Zhang, Jinlong. "Chiral Br?nsted acid-catalyzed dynamic kinetic resolution of atropisomeric: Ortho -formyl naphthamides". supporting information. p. 7265 - 7268. Retrieved 2020/07/14.
• 2、 Zengin, Gulay,Mert, Adem,Zengin, Huseyin. "Synthesis, evaluation of antimicrobial activity and theoretical analyses of novel sulfathiazole derivatives". . p. 1 - 11. Retrieved 2019/01/16.