3,4-DIETHOXYBENZOIC ACID ETHYL ESTER

Base Information

• Chemical Name: 3,4-DIETHOXYBENZOIC ACID ETHYL ESTER
• CAS No.: 75332-44-4
• Molecular Formula: C13H18 O4
• Molecular Weight: 238.284
• Mol file: 75332-44-4.mol

Synonyms:3,4-Diethoxybenzoicacid ethyl ester; Ethyl 3,4-diethoxybenzoate

Chemical Property of 3,4-DIETHOXYBENZOIC ACID ETHYL ESTER

Chemical Property:

• Vapor Pressure: 0.000156mmHg at 25°C
• Melting Point: 54-58 °C(lit.)
• Refractive Index: 1.492
• Boiling Point: 331.4°C at 760 mmHg
• Flash Point: 230 °F
• PSA: 44.76000
• Density: 1.059g/cm³
• LogP: 2.66070
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99%min ^*data from raw suppliers

Ethyl3,4-Diethoxybenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-DIETHOXYBENZOIC ACID ETHYL ESTER

There total 7 articles about 3,4-DIETHOXYBENZOIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

ethanol (64-17-5) + 3,4-diethoxybenzoic acid (5409-31-4) → 3,4-diethoxybenzoic acid ethyl ester (75332-44-4)

Guidance literature:

With sulfuric acid; In benzene; for 12h; Reflux;

DOI:10.1002/hlca.201100128

Reference yield: 90.0%

→ 3,4-diethoxybenzoic acid ethyl ester (75332-44-4)

Guidance literature:

Reference yield:

3,4-diethoxy-benzoic acid ; calcium compound → 2-Ethoxyphenol (94-71-3) + 3,4-diethoxybenzoic acid ethyl ester (75332-44-4) + benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9)

Guidance literature:

bei der trocknen Destillation;

upstream raw materials:

3,4-Dihydroxybenzoic acid

ethyl iodide

ethyl bromide

Ethyl protocatechuate

Downstream raw materials:

C₁₅H₂₄O₃

ethyl 2-bromo-4,5-diethoxybenzoate

2-(2-bromo-4,5-diethoxyphenyl)propan-2-ol

1-bromo-4,5-diethoxy-2-(1-methylethenyl)benzene

Refernces

• 1、 Miao, Hua-Ming,Zhao, Gui-Long,Zhang, Lin-Shan,Shao, Hua,Wang, Jian-Wu. "Exquisite synthesis of a designed PAR-1 antagonist". experimental part. p. 1981 - 1993. Retrieved 2012/01/04.
• 2、 Rowe, Kathryn E.,Bruce, Duncan W.. "The synthesis and mesomorphism of di-, tetra- and hexa-catenar liquid crystals based on 2,2′-bipyridine". . p. 331 - 341. Retrieved 2007/10/03.