Technology Process of (E)-1-(4-chlorophenyl)-3-(2,3,5,6-tetrafluoro-4-methoxyphenyl)prop-1-ene
There total 7 articles about (E)-1-(4-chlorophenyl)-3-(2,3,5,6-tetrafluoro-4-methoxyphenyl)prop-1-ene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: diisobutylaluminium hydride / toluene / 1 h / -78 °C / Inert atmosphere
2: phosphorus tribromide / diethyl ether / 1 h / 0 °C / Inert atmosphere
3: Triphenylphosphine oxide / hexane; tetrahydrofuran / 16 h / 75 °C / Schlenk technique; Inert atmosphere
With
phosphorus tribromide; diisobutylaluminium hydride; Triphenylphosphine oxide;
In
tetrahydrofuran; diethyl ether; hexane; toluene;
DOI:10.1016/j.tet.2015.05.107
- Guidance literature:
-
With
Triphenylphosphine oxide;
In
tetrahydrofuran; hexane;
at 75 ℃;
for 16h;
chemoselective reaction;
Schlenk technique;
Inert atmosphere;
DOI:10.1016/j.tet.2015.05.107
- Guidance literature:
-
Multi-step reaction with 2 steps
1: phosphorus tribromide / diethyl ether / 1 h / 0 °C / Inert atmosphere
2: Triphenylphosphine oxide / hexane; tetrahydrofuran / 16 h / 75 °C / Schlenk technique; Inert atmosphere
With
phosphorus tribromide; Triphenylphosphine oxide;
In
tetrahydrofuran; diethyl ether; hexane;
DOI:10.1016/j.tet.2015.05.107