3,3,5-triphenyl-2,3-dihydro-1H-2-pyrrolone

Base Information

• Chemical Name: 3,3,5-triphenyl-2,3-dihydro-1H-2-pyrrolone
• CAS No.: 28172-27-2
• Molecular Formula: C₂₂H₁₇NO
• Molecular Weight: 311.383
• Mol file: 28172-27-2.mol

Synonyms:3,3,5-triphenyl-2,3-dihydro-1H-2-pyrrolone

Chemical Property of 3,3,5-triphenyl-2,3-dihydro-1H-2-pyrrolone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,3,5-triphenyl-2,3-dihydro-1H-2-pyrrolone

There total 9 articles about 3,3,5-triphenyl-2,3-dihydro-1H-2-pyrrolone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2,3,5-triphenyl-2H-pyrrol-2-ol → 3,3,5-triphenyl-2,3-dihydro-1H-2-pyrrolone (28172-27-2)

Guidance literature:

With oxygen; sodium t-butanolate; In dimethyl sulfoxide; at 25 ℃; for 4h; Green chemistry;

DOI:10.1002/adsc.201800845

Reference yield: 91.0%

2,4,5-triphenylpyrrole (3274-61-1) → 3,3,5-triphenyl-2,3-dihydro-1H-2-pyrrolone (28172-27-2)

Guidance literature:

With oxygen; sodium t-butanolate; In dimethyl sulfoxide; at 25 ℃; for 4h; Solvent; Reagent/catalyst; Temperature; Time; Green chemistry;

DOI:10.1002/adsc.201800845

Reference yield: 75.0%

3-(benzylamino)-1,3-diphenylprop-2-en-1-one (20964-95-8) → 3,3,5-triphenyl-2,3-dihydro-1H-2-pyrrolone (28172-27-2)

Guidance literature:

3-(benzylamino)-1,3-diphenylprop-2-en-1-one; With potassium phosphate; In dimethyl sulfoxide; at 140 ℃; for 12h; Inert atmosphere; Green chemistry;

With oxygen; sodium t-butanolate; In dimethyl sulfoxide; at 25 ℃; for 4h; Green chemistry;

DOI:10.1002/adsc.201800845

upstream raw materials:

1,2,3,5-tetraphenyl-pyrrole

1-benzyl-2,3,5-triphenyl-1H-pyrrole

(Z)-1,2,4-triphenyl-2-butene-1,4-dione

2,4,5-triphenylpyrrole

Refernces

• 1、 Huang, Huabin,Hu, Bing,Lai, Yuanfa,Zou, Zhongai,Lin, Huixia,Xiao, Yujuan,You, Qihua,Shen, Jinhai. "Base-Promoted Oxidative Dearomatization of Pyrroles to 4-Pyrrolin-2-ones". supporting information. p. 3906 - 3910. Retrieved 2018/09/21.
• 2、 Rao, H Surya Prakash,Gorityala, Bala Kishan,Vasantham. "Studies in microwave mediated solvent-free synthesis of 5-aryl-2,3-diphenylpyrroles from 4-aryl-1,2-diphenyl-2-butene-1,4-diones". . p. 1470 - 1474. Retrieved 2008/09/18.