(4-aminobenzene-1,3-diyl)dimethanol

Base Information

• Chemical Name: (4-aminobenzene-1,3-diyl)dimethanol
• CAS No.: 1009314-88-8
• Molecular Formula: C₈H₁₁NO₂
• Molecular Weight: 153.181
• Mol file: 1009314-88-8.mol

Synonyms:4-amino-3-(hydroxymethyl)phenylmethanol

Chemical Property of (4-aminobenzene-1,3-diyl)dimethanol

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

[4-Amino-3-(hydroxymethyl)phenyl]methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-aminobenzene-1,3-diyl)dimethanol

There total 3 articles about (4-aminobenzene-1,3-diyl)dimethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

C20H39NO2Si2 (1055310-33-2) → 4-amino-3-(hydroxymethyl)phenylmethanol (1009314-88-8)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1039/b808198k

Reference yield:

2,4-bishydroxymethyl nitrobenzene (1253261-36-7) → 4-amino-3-(hydroxymethyl)phenylmethanol (1009314-88-8)

Guidance literature:

With palladium on carbon; hydrogen; In ethanol; ethyl acetate; for 4h;

DOI:10.1021/ol102081q

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + aniline (62-53-3) → 4-amino-3-(hydroxymethyl)phenylmethanol (1009314-88-8)

Guidance literature:

With sodium hydroxide; In water; N,N-dimethyl-formamide; at 60 ℃; for 4h; pH=9;

DOI:10.1080/00958972.2011.636426

upstream raw materials:

C₂₀H₃₉NO₂Si₂

2,4-bishydroxymethyl nitrobenzene

formaldehyd

aniline

Downstream raw materials:

C₂₄H₂₉NO₂Si

C₃₇H₄₀N₂O₁₉

Refernces

• 1、 Polaske, Nathan W.,Szalai, Michael L.,Shanahan, Charles S.,McGrath, Dominic V.. "Convergent synthesis of geometrically disassembling dendrimers using Cu(I)-catalyzed C-O bond formation". supporting information; experimental part. p. 4944 - 4947. Retrieved 2010/12/25.