C₂₀H₂₃N₇O₃S

Base Information

• Chemical Name: C₂₀H₂₃N₇O₃S
• CAS No.: 1338084-34-6
• Molecular Formula: C₂₀H₂₃N₇O₃S
• Molecular Weight: 441.514
• Mol file: 1338084-34-6.mol

Synonyms:C₂₀H₂₃N₇O₃S

Chemical Property of C₂₀H₂₃N₇O₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₂₀H₂₃N₇O₃S

There total 5 articles about C₂₀H₂₃N₇O₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

O-2-tetrahydro-2H-pyranhydroxylamine (6723-30-4) + C15H14N6O2S (1338084-35-7) → C20H23N7O3S (1338084-34-6)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.bmcl.2011.08.022

Reference yield:

C17H18N6O2S (1338084-01-7) → C20H23N7O3S (1338084-34-6)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol; sodium hydroxide / 20 °C / Reflux

2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C / Inert atmosphere

With ethanol; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; In dichloromethane;

DOI:10.1016/j.bmcl.2011.08.022

Reference yield:

5-(4-(dimethylamino)phenyl)-1,3,4-thiadiazol-2-amine (3121-63-9) → C20H23N7O3S (1338084-34-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 5 - 20 °C / Inert atmosphere

1.2: 5 °C / Inert atmosphere

2.1: ethanol; sodium hydroxide / 20 °C / Reflux

3.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C / Inert atmosphere

With ethanol; sodium hydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; In tetrahydrofuran; dichloromethane; mineral oil;

DOI:10.1016/j.bmcl.2011.08.022

upstream raw materials:

O-2-tetrahydro-2H-pyranhydroxylamine

C₁₅H₁₄N₆O₂S

C₁₇H₁₈N₆O₂S

5-(4-(dimethylamino)phenyl)-1,3,4-thiadiazol-2-amine

Downstream raw materials:

C₁₅H₁₅N₇O₂S

Refernces