2-Bromo-N,N-diethylbenzenesulphonamide

Base Information

• Chemical Name: 2-Bromo-N,N-diethylbenzenesulphonamide
• CAS No.: 65000-12-6
• Molecular Formula: C10H14BrNO2S
• Molecular Weight: 292.197
• Hs Code.: 2935009090
• Mol file: 65000-12-6.mol

Synonyms:2-Bromo-N,N-diethylbenzenesulphonamide;2-Bromo-N,N-diethylbenzenesulfonamide;N,N-Diethyl 2-bromobenzenesulfonamide

Chemical Property of 2-Bromo-N,N-diethylbenzenesulphonamide

Chemical Property:

• Vapor Pressure: 1.57E-05mmHg at 25°C
• Melting Point: 76-78 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
• Refractive Index: 1.556
• Boiling Point: 365.4 °C at 760 mmHg
• PKA: -5.61±0.70(Predicted)
• Flash Point: 174.8 °C
• PSA: 45.76000
• Density: 1.431 g/cm³
• LogP: 3.56040
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

2-Bromo-N,N-diethylbenzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Bromo-N,N-diethylbenzenesulphonamide

There total 7 articles about 2-Bromo-N,N-diethylbenzenesulphonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

o-bromobenzenesulfonyl chloride (2905-25-1) + diethylamine (109-89-7) → 2-bromo-N,N-diethylbenzenesulfonamide (65000-12-6)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1021/acs.orglett.6b03741

Reference yield: 72.0%

o-bromobenzenesulfonyl chloride (2905-25-1) + triethylamine (121-44-8) → 2-bromo-N,N-diethylbenzenesulfonamide (65000-12-6)

Guidance literature:

With sodium sulfate; In water; at 20 ℃; for 3.2h; Electrochemical reaction;

DOI:10.1039/c7gc03141f

Reference yield: 70.0%

ortho-bromobenzenesulfonyl hydrazide (60199-33-9) + triethylamine (121-44-8) → 2-bromo-N,N-diethylbenzenesulfonamide (65000-12-6)

Guidance literature:

With sodium sulfate; In water; acetonitrile; at 20 ℃; for 9h; Electrochemical reaction;

DOI:10.1039/c7gc03141f

upstream raw materials:

o-bromobenzenesulfonyl chloride

diethylamine

bromobenzene

2-bromoaniline

Downstream raw materials:

N-ethyl-N-vinylbenzenesulfonamide

Refernces

• 1、 Sheykhan,Khani,Abbasnia,Shaabanzadeh,Joafshan. "An approach to C-N activation: Coupling of arenesulfonyl hydrazides and arenesulfonyl chlorides with: Tert -amines via a metal-, oxidant- and halogen-free anodic oxidation". supporting information. p. 5940 - 5948. Retrieved 2017/12/26.
• 2、 Bheeter, Charles B.,Jin, Rongwei,Bera, Jitendra K.,Dixneuf, Pierre H.,Doucet, Henri. "Palladium-catalysed dehydrogenative sp3 C-H bonds functionalisation into alkenes: A direct access to N-alkenylbenzenesulfonamides". supporting information. p. 119 - 124. Retrieved 2014/03/21.