Hydroxypinacolone Retinoate

Base Information

• Chemical Name: Hydroxypinacolone Retinoate
• CAS No.: 893412-73-2
• Molecular Formula: C₂₆H₃₈O₃
• Molecular Weight: 398.586
• Mol file: 893412-73-2.mol

Synonyms:MDI101

Chemical Property of Hydroxypinacolone Retinoate

Chemical Property:

• Boiling Point: 508.5±33.0 °C(Predicted)
• PSA: 43.37000
• Density: 0.990±0.06 g/cm3(Predicted)
• LogP: 6.67640

Purity/Quality:

99.3% ^*data from raw suppliers

RetinoicAcid3,3-Dimethyl-2-oxobutylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Retinoic Acid 3,3-Dimethyl-2-oxobutyl Ester, is a Retinoic Acid derivative that has shown to be used for treatment of dermatological disorders.

Technology Process of Hydroxypinacolone Retinoate

There total 1 articles about Hydroxypinacolone Retinoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-hydroxy-3,3-dimethylbutan-2-one (38895-88-4) + all-trans-retinoic-acid (302-79-4) → MDI-101 (893412-73-2)

Guidance literature:

all-trans-retinoic-acid; With dmap; dicyclohexyl-carbodiimide; In tetrahydrofuran; at -5 - 5 ℃; for 0.5h;

1-hydroxy-3,3-dimethylbutan-2-one; In tetrahydrofuran; at 10 ℃; for 8h; Temperature; Reagent/catalyst;

upstream raw materials:

1-hydroxy-3,3-dimethylbutan-2-one

all-trans-retinoic-acid

Refernces