1-Methylcyclohexanamine

Base Information

• Chemical Name: 1-Methylcyclohexanamine
• CAS No.: 6526-78-9
• Molecular Formula: C7H15N
• Molecular Weight: 113.203
• Hs Code.: 2921300090
• European Community (EC) Number: 685-740-8
• DSSTox Substance ID: DTXSID60388558
• Nikkaji Number: J503.246F
• Wikidata: Q72489650
• Mol file: 6526-78-9.mol

Synonyms:1-methylcyclohexanamine;6526-78-9;1-methylcyclohexan-1-amine;1-AMINO-1-METHYLCYCLOHEXANE;1-METHYL-CYCLOHEXYLAMINE;(1-methylcyclohexyl)amine;amino-methylcyclohexane;1-methylcyclohexaneamine;1,4-methylcyclohexylamine;1-methyl-1-cyclohexylamine;SCHEMBL8919;(1-methyl-cyclohexyl)-amine;DTXSID60388558;YDBHSDRXUCPTQQ-UHFFFAOYSA-N;MFCD08061940;AKOS002392013;SB38137;AM804197;BS-12854;CS-0279384;FT-0755148;EN300-43234;W10115;AB00173406-02;A835042

Chemical Property of 1-Methylcyclohexanamine

Chemical Property:

• Melting Point: 39-40ºC
• Refractive Index: 1.4547 (13℃)
• Boiling Point: 148.3 °C at 760 mmHg
• PKA: 10.95±0.70(Predicted)
• Flash Point: 27.5 °C
• PSA: 26.02000
• Density: 0.854 g/cm³
• LogP: 2.36820
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 113.120449483
• Heavy Atom Count: 8
• Complexity: 72.5

Purity/Quality:

98%Min ^*data from raw suppliers

1-Methylcyclohexanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CCCCC1)N

Technology Process of 1-Methylcyclohexanamine

There total 19 articles about 1-Methylcyclohexanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dibutyl ether (142-96-1) + cycloheptanol (502-41-0) + sulfuric acid (7664-93-9) + potassium cyanide (151-50-8) → cycloheptanamine (5452-35-7) + 1-methyl-1-cyclohexylamine (6526-78-9)

Guidance literature:

Erhitzen des Reaktionsprodukts mit konz. wss. Salzsaeure;

Reference yield:

1-Methyl-1-nitrocyclohexane (59368-15-9) → 1-methyl-1-cyclohexylamine (6526-78-9)

Guidance literature:

With hydrogenchloride; tin;

Reference yield:

1-methyl-1-cyclohexylformamide (101253-12-7) → 1-methyl-1-cyclohexylamine (6526-78-9)

Guidance literature:

With sodium hydroxide; In ethanol;

upstream raw materials:

1-methyl-1-cyclohexanecarboxylic acid

1-Methylcyclohexanol

potassium cyanide

1-Methyl-1-nitrocyclohexane

Downstream raw materials:

1-(2-Chloro-ethyl)-3-(1-methyl-cyclohexyl)-urea

1-Nitroso-1-methyl-cyclohexan

N-<1-Methyl-cyclohexyl>-hydroxylamin

1,3,5,7-tetra(1-methylcyclohexyl)-2,4,6,8-tetrachloro-cyclo-1,3,5,7-tetraaza-2,4,6,8-tetraborane

Refernces

• 1、 -. "Novel treatment for alzheimer's disease". . . Retrieved 2009/11/30.
• 2、 -. "Methods and compositions for treating amyloid-related diseases". Page/Page column 140-141. . Retrieved 2010/11/24.