10,12-DOCOSADIYNEDIOIC ACID

Base Information

• Chemical Name: 10,12-DOCOSADIYNEDIOIC ACID
• CAS No.: 28393-02-4
• Molecular Formula: C22H34O4
• Molecular Weight: 362.51
• Hs Code.: 2917190090
• Mol file: 28393-02-4.mol

Synonyms:Docosadeca-10,12-diynedioic acid;Docosa-10,12-diyndioicacid;docosa-10,12-diynedioic acid;

Chemical Property of 10,12-DOCOSADIYNEDIOIC ACID

Chemical Property:

• Vapor Pressure: 2.52E-14mmHg at 25°C
• Melting Point: 110-112 °C
• Refractive Index: 1.505
• Boiling Point: 566.7 °C at 760 mmHg
• PKA: 4.48±0.10(Predicted)
• Flash Point: 310.6 °C
• PSA: 74.60000
• Density: 1.043 g/cm³
• LogP: 5.40400
• Sensitive.: Light Sensitive
• Water Solubility.: Insoluble in water.

Purity/Quality:

98%Min ^*data from raw suppliers

DOCOSADIYNEDIOICACID ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Polymerizable diacid (10,12-docosadiynedioic acid) was used as obtained from GFS Chemicals. Synthesis of dimesogenic liquid crystals with both cholesterol and azobenzene groups is by the esterification of 10,12-docosadiynedioic acid. .

Technology Process of 10,12-DOCOSADIYNEDIOIC ACID

There total 6 articles about 10,12-DOCOSADIYNEDIOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

undec-10-ynoic acid (2777-65-3) → 10,12-docosadiynedioic acid (28393-02-4)

Guidance literature:

With oxygen; ammonium chloride; copper(l) chloride; In water; at 20 ℃;

DOI:10.1039/c2jm16273c

Reference yield:

11-bromo-10-undecynoic acid (13030-63-2) + 3-(1,1,7-trihydroperfluoroheptyloxy)-1-propyne (140427-89-0) → 10,12-docosadiynedioic acid (28393-02-4) + 14-(1,1,7-trihydroperfluoroheptyloxy)tetradecane-10,12-diynoic acid (140427-97-0)

Guidance literature:

With hydroxylamine hydrochloride; methylamine; copper(l) chloride; Multistep reaction. Yields of byproduct given; 1.) methanol, 2.) methanol, 4 h;

Reference yield:

2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-1-heptanol (335-99-9) → 10,12-docosadiynedioic acid (28393-02-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / benzyltrimethylammonium chloride, 40percent aq. KOH / benzene / 8 h / 20 - 60 °C

2: 1.) CuCl, NH₂OH*HCl, MeNH₂ / 1.) methanol, 2.) methanol, 4 h

With potassium hydroxide; hydroxylamine hydrochloride; benzyltrimethylammonium chloride; methylamine; copper(l) chloride; In benzene;

upstream raw materials:

undec-10-ynoic acid

11-bromo-10-undecynoic acid

3-(1,1,7-trihydroperfluoroheptyloxy)-1-propyne

2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-1-heptanol

Downstream raw materials:

10,12-docosadiyndioic acid dimethyl ester

1-ethyl-3-(3-dimethylaminopropyl)carbodiimide

Refernces

• 1、 Eaidkong, Thichamporn,Mungkarndee, Radeemada,Phollookin, Chaiwat,Tumcharern, Gamonwarn,Sukwattanasinitt, Mongkol,Wacharasindhu, Sumrit. "Polydiacetylene paper-based colorimetric sensor array for vapor phase detection and identification of volatile organic compounds". experimental part. p. 5970 - 5977. Retrieved 2012/06/18.
• 2、 Ozcayir, Y.,Blumstein, A.. "Diacetylenic Liquid Crystalline Diesters". . p. 237 - 246. Retrieved 2007/10/02.