P-CHLOROPROPYLBENZENE

Base Information

• Chemical Name: P-CHLOROPROPYLBENZENE
• CAS No.: 52944-34-0
• Molecular Formula: C9H11Cl
• Molecular Weight: 154.639
• Hs Code.: 2903999090
• Mol file: 52944-34-0.mol

Synonyms:P-CHLOROPROPYLBENZENE;4-CHLOROPROPYLBENZENE;4-PROPYLCHLOROBENZENE;1-CHLORO-4-PROPYLBENZENE

Chemical Property of P-CHLOROPROPYLBENZENE

Chemical Property:

• Vapor Pressure: 0.405mmHg at 25°C
• Refractive Index: 1.513
• Boiling Point: 203°Cat760mmHg
• Flash Point: 74.4°C
• PSA: 0.00000
• Density: 1.026g/cm³
• LogP: 3.29250
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Chloro-4-propylbenzene ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,N,Xn
• Statements: 36/37/38-50/53-22
• Safety Statements: 26-36/37/39-61-60

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of P-CHLOROPROPYLBENZENE

There total 15 articles about P-CHLOROPROPYLBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-(4-chloro-phenyl)-5,5-dimethyl-[1,3,2]dioxaborinane (827605-29-8) + propyl tosylate (599-91-7) → 1-chloro-4-propylbenzene (52944-34-0)

Guidance literature:

With copper(l) iodide; lithium tert-butoxide; In N,N-dimethyl-formamide; at 60 ℃; for 12h; Inert atmosphere;

DOI:10.1002/anie.201008007

Reference yield: 83.0%

4'-chloropropiophenone (6285-05-8) → 1-chloro-4-propylbenzene (52944-34-0)

Guidance literature:

With polymethylhydrosiloxane; tris(pentafluorophenyl)borate; In dichloromethane; at 20 ℃;

DOI:10.1021/jo0204045

Reference yield: 48.0%

2-(4-chloro-phenyl)-5,5-dimethyl-[1,3,2]dioxaborinane (827605-29-8) + 1-Chloropropane (540-54-5) → 1-chloro-4-propylbenzene (52944-34-0)

Guidance literature:

With copper(l) iodide; lithium tert-butoxide; In N,N-dimethyl-formamide; at 110 ℃; for 24h; Inert atmosphere;

DOI:10.1002/anie.201008007

upstream raw materials:

4'-chloropropiophenone

phenylpropane

1-(4-chlorophenyl)-2,2-dichloro-1-propanone

para-dichlorobenzene

Downstream raw materials:

cis-(1R,2R)-1,2-dihydroxy-6-chloro-3-propylcyclohexa-3,5-diene

phenylpropane

p-chloro(methylstyrene)

1-(4-Chlorophenyl)-1-propyl acetate

Refernces

• 1、 McKeown, Bradley A.,Prince, Bruce M.,Ramiro, Zoraida,Gunnoe, T. Brent,Cundari, Thomas R.. "PtII-catalyzed hydrophenylation of α-olefins: Variation of linear/branched products as a function of ligand donor ability". . p. 1607 - 1615. Retrieved 2014/05/20.
• 2、 Gu, Weixing,Haneline, Mason R.,Douvris, Christos,Ozerov, Oleg V.. "Carbon-carbon coupling of C(sp3)-F bonds using alumenium catalysis". experimental part. p. 11203 - 11212. Retrieved 2009/12/05.