Technology Process of N-(1-(1H-benzo[d][1,2,3]triazol-1-yl)ethyl)-4-bromoaniline
There total 1 articles about N-(1-(1H-benzo[d][1,2,3]triazol-1-yl)ethyl)-4-bromoaniline which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
toluene;
at 20 ℃;
for 12h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: boron trifluoride diethyl etherate / tetrahydrofuran / 0.25 h / -15 °C
1.2: 2 h / -5 °C
2.1: pyridine / dichloromethane / 2 h / 0 °C
3.1: sodium carbonate / tetrakis(triphenylphosphine) palladium(0) / 1,2-dimethoxyethane / 2 h / Reflux; Inert atmosphere
4.1: acetic acid; sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 2 h / 20 °C
With
pyridine; boron trifluoride diethyl etherate; sodium tris(acetoxy)borohydride; sodium carbonate; acetic acid;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; 1,2-dichloro-ethane;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: boron trifluoride diethyl etherate / tetrahydrofuran / 0.25 h / -15 °C
1.2: 2 h / -5 °C
2.1: pyridine / dichloromethane / 2 h / 0 °C
3.1: sodium carbonate / tetrakis(triphenylphosphine) palladium(0) / 1,2-dimethoxyethane / 2 h / Reflux; Inert atmosphere
4.1: acetic acid; sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 2 h / 20 °C
5.1: hydrogenchloride / methanol / 2 h / Reflux
With
pyridine; hydrogenchloride; boron trifluoride diethyl etherate; sodium tris(acetoxy)borohydride; sodium carbonate; acetic acid;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane; 1,2-dichloro-ethane;