1-(3-HYDROXYPHENYL)-1-METHOXY-1-(2-THIAZOLYL)-PROPANE

Base Information Edit

Chemical Name:1-(3-HYDROXYPHENYL)-1-METHOXY-1-(2-THIAZOLYL)-PROPANE
CAS No.:129424-07-3
Molecular Formula:C13H15 N O2 S
Molecular Weight:249.334
Hs Code.:
Mol file:129424-07-3.mol

Synonyms:1-(3-HYDROXYPHENYL)-1-METHOXY-1-(2-THIAZOLYL)-PROPANE

Suppliers and Price of 1-(3-HYDROXYPHENYL)-1-METHOXY-1-(2-THIAZOLYL)-PROPANE

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(3-HYDROXYPHENYL)-1-METHOXY-1-(2-THIAZOLYL)-PROPANE 95.00%
5MG
$ 497.56

Total 2 raw suppliers

Chemical Property of 1-(3-HYDROXYPHENYL)-1-METHOXY-1-(2-THIAZOLYL)-PROPANE Edit

Chemical Property:

Boiling Point:386.2±37.0 °C(Predicted)
PKA:9.59±0.10(Predicted)
PSA：70.59000
Density:1.206±0.06 g/cm3(Predicted)
LogP:3.14870

Purity/Quality:

98%min ^*data from raw suppliers

1-(3-HYDROXYPHENYL)-1-METHOXY-1-(2-THIAZOLYL)-PROPANE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(3-HYDROXYPHENYL)-1-METHOXY-1-(2-THIAZOLYL)-PROPANE

There total 11 articles about 1-(3-HYDROXYPHENYL)-1-METHOXY-1-(2-THIAZOLYL)-PROPANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 134154-14-6
1-<3-(benzyloxy)phenyl>-1-(thiazol-2-yl)propyl methyl ether

: 129424-07-3
3-<1-methoxy-1-(thiazol-2-yl)propyl>phenol

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate;
DOI:10.1021/jm00111a038

Reference yield: 76.0%

: 131610-00-9
1-<3-<(tert-butyldimethylsilyl)oxy>phenyl>-1-(thiazol-2-yl)propyl methyl ether

: 129424-07-3
3-<1-methoxy-1-(thiazol-2-yl)propyl>phenol

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 2h; Ambient temperature;
DOI:10.1021/jm00111a038

Reference yield:

: 100-83-4
meta-hydroxybenzaldehyde

: 129424-07-3
3-<1-methoxy-1-(thiazol-2-yl)propyl>phenol

Guidance literature:: Multi-step reaction with 6 steps

1: 93 percent / K₂CO₃ / dimethylformamide / 18 h / Ambient temperature

2: 1.) n-BuLi / 1.) THF, hexane, -70 deg C, 2.) THF, hexane, from -70 deg C to RT, 2.5 h

3: 100 percent / DMSO, oxalyl chloride / CH₂Cl₂ / 0.25 h / -55 - -50 °C

4: 91 percent / diethyl ether / 1 h / Ambient temperature

5: 1.) NaH / 1.) THF, 2.) THF, RT, 2 h

6: 76 percent / H₂ / 30percent Pd/C / ethyl acetate

With n-butyllithium; oxalyl dichloride; hydrogen; sodium hydride; potassium carbonate; dimethyl sulfoxide; palladium on activated charcoal; In diethyl ether; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm00111a038