(1S,2S)-2-METHOXYCYCLOHEXANOL, CHIPROS\(TM, 99% EE 98

Base Information

• Chemical Name: (1S,2S)-2-METHOXYCYCLOHEXANOL, CHIPROS\(TM, 99% EE 98
• CAS No.: 134108-68-2
• Molecular Formula: C₇H₁₄O₂
• Molecular Weight: 130.187
• Mol file: 134108-68-2.mol

Synonyms:(1S,2S)-2-METHOXYCYCLOHEXANOL, CHIPROS\(TM, 99% EE 98

Chemical Property of (1S,2S)-2-METHOXYCYCLOHEXANOL, CHIPROS\(TM, 99% EE 98

Chemical Property:

• PSA: 29.46000
• Density: 1.015
• LogP: 0.93630

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s): R36/38:Irritating to eyes and skin.
• Hazard Codes: R36/38:Irritating to eyes and skin.
• Statements: R36/38:Irritating to eyes and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36:Wear suitable prot

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1S,2S)-2-METHOXYCYCLOHEXANOL, CHIPROS\(TM, 99% EE 98

There total 36 articles about (1S,2S)-2-METHOXYCYCLOHEXANOL, CHIPROS\(TM, 99% EE 98 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methanol (67-56-1) + cyclohexane-1,2-epoxide (286-20-4) → trans-2-methoxycyclohexanol (7429-40-5,7429-41-6,113625-71-1,134108-68-2,134108-92-2,2979-24-0)

Guidance literature:

With trichloro(trifluoromethanesulfonato)titanium(IV); for 0.17h; Heating;

DOI:10.1080/00397919908086066

Reference yield: 97.0%

2-methoxy-cyclohex-3-enol → trans-2-methoxycyclohexanol (7429-40-5,7429-41-6,113625-71-1,134108-68-2,134108-92-2,2979-24-0)

Guidance literature:

With hydrogen; platinum on activated charcoal; In ethyl acetate;

DOI:10.1021/ol0060782

Reference yield: 95.0%

methanol (67-56-1) + cyclohexene oxide (286-20-4) → trans-2-methoxycyclohexanol (7429-40-5,7429-41-6,113625-71-1,134108-68-2,134108-92-2,2979-24-0)

Guidance literature:

With Cu(bpy)(H₂O)(BF₄)2(bpy); at 20 ℃; for 9h;

DOI:10.1016/j.jcat.2008.05.021

upstream raw materials:

trans-2-chlorocyclohexanol

(+/-)-trans-1-acetoxy-2-methyoxycyclohexane

methanol

cyclohexane-1,2-epoxide

Downstream raw materials:

Bis-(trans-2-methoxycyclohexyl)carbonat

trans-2-methoxycyclohexyl butanoate

cis-2-methoxy-1-chlorocyclohexane

2-methoxycyclohexanone

Refernces

• 1、 Rahmatpour, Ali,Zamani, Maryam. "MBA-cross-linked poly(N-vinyl-2-pyrrolidone)/ferric chloride macromolecular coordination complex as a novel and recyclable Lewis acid catalyst: Synthesis, characterization, and performance toward for regioselective ring-opening alcoholysis of epoxides". . . Retrieved 2021/09/30.
• 2、 Shi, Xian-Lei,Sun, Benyu,Hu, Qianqian,Chen, Yongju,Duan, Peigao. "Fiber-supported Fe(iii) complex catalyst in spinning basket reactor for cleaner ring-opening of epoxides with alcohols". . p. 3573 - 3582. Retrieved 2019/07/09.