Oxirane, 2-(1-fluoro-2-methylpropyl)-3-(1-methylethyl)-, [2alpha(R*),3ba]- (9CI)

Base Information

• Chemical Name: Oxirane, 2-(1-fluoro-2-methylpropyl)-3-(1-methylethyl)-, [2alpha(R*),3ba]- (9CI)
• CAS No.: 138809-46-8
• Molecular Formula: C₉H₁₇FO
• Molecular Weight: 160.232
• Mol file: 138809-46-8.mol

Synonyms:Oxirane, 2-(1-fluoro-2-methylpropyl)-3-(1-methylethyl)-, [2alpha(R*),3b閠a]- (9CI);Oxirane,2-(1-fluoro-2-methylpropyl)-3-(1-methylethyl)-,[2alpha(R*),3bta]-(9CI)

Chemical Property of Oxirane, 2-(1-fluoro-2-methylpropyl)-3-(1-methylethyl)-, [2alpha(R*),3ba]- (9CI)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of Oxirane, 2-(1-fluoro-2-methylpropyl)-3-(1-methylethyl)-, [2alpha(R*),3ba]- (9CI)

There total 4 articles about Oxirane, 2-(1-fluoro-2-methylpropyl)-3-(1-methylethyl)-, [2alpha(R*),3ba]- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-5-Fluoro-2,6-dimethyl-hept-3-ene (138710-22-2) → (2R,3S)-2-((S)-1-Fluoro-2-methyl-propyl)-3-isopropyl-oxirane (138710-25-5,138809-46-8) + (2R,3S)-2-((R)-1-Fluoro-2-methyl-propyl)-3-isopropyl-oxirane (138710-25-5,138809-46-8)

Guidance literature:

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 48h; Yield given. Yields of byproduct given;

DOI:10.1016/0040-4039(91)80168-6

Reference yield:

(E)-5-Fluoro-2,6-dimethyl-hept-3-ene (138710-22-2) → (2R,3S)-2-((S)-1-Fluoro-2-methyl-propyl)-3-isopropyl-oxirane (138710-25-5,138809-46-8) + (2R,3S)-2-((R)-1-Fluoro-2-methyl-propyl)-3-isopropyl-oxirane (138710-25-5,138809-46-8)

Guidance literature:

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 48h; Yield given. Yields of byproduct given;

DOI:10.1016/0040-4039(91)80168-6

Reference yield:

(+/-)-(E)-2,6-dimethylhept-4-en-3-ol (121440-79-7) → (2R,3R)-2-((R)-1-Fluoro-2-methyl-propyl)-3-isopropyl-oxirane (138710-25-5,138809-46-8) + (2R,3S)-2-((R)-1-Fluoro-2-methyl-propyl)-3-isopropyl-oxirane (138710-25-5,138809-46-8)

Guidance literature:

With sodium hydroxide; N-Bromosuccinimide; NBS-Et₂NH*3HF; Multistep reaction;

DOI:10.1016/0040-4039(91)80168-6

upstream raw materials:

(+/-)-(E)-2,6-dimethylhept-4-en-3-ol

(E)-5-Fluoro-2,6-dimethyl-hept-3-ene

Refernces