ALPHA-D-ARABINOPYRANOSYL AZIDE

Base Information

• Chemical Name: ALPHA-D-ARABINOPYRANOSYL AZIDE
• CAS No.: 138892-04-3
• Molecular Formula: C5H9N3O4
• Molecular Weight: 175.14266
• Mol file: 138892-04-3.mol

Synonyms:ALPHA-D-ARABINOPYRANOSYL AZIDE;a-D-Arabinopyranosylazide

Chemical Property of ALPHA-D-ARABINOPYRANOSYL AZIDE

Chemical Property:

• PSA: 119.67000
• LogP: -1.81154

Purity/Quality:

ALPHA-D-ARABINOPYRANOSYL AZIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ALPHA-D-ARABINOPYRANOSYL AZIDE

There total 1 articles about ALPHA-D-ARABINOPYRANOSYL AZIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,3,4-Tri-O-acetyl-α-D-arabinopyranosyl azide → α-D-Arabinopyranosyl azide (138892-04-3)

Guidance literature:

With sodium methylate; In methanol; for 2h; Ambient temperature;

DOI:10.1055/s-1991-26641

Reference yield: 84.0%

prop-2-ynyl 4-sulfamoylbenzoate (915694-58-5) + α-D-Arabinopyranosyl azide (138892-04-3) → 4-({[4-(aminosulfonyl)benzoyl]oxy}methyl)-1-(α-D-arabinopyranosyl)-1H-1,2,3-triazole

Guidance literature:

With copper(II) sulfate; sodium L-ascorbate; In water; tert-butyl alcohol; at 40 ℃;

DOI:10.1021/jm060967z

Reference yield:

α-D-Arabinopyranosyl azide (138892-04-3) → 2,2-Dimethyl-propionic acid (2S,3S,4R,5R)-2-[((R)-1-tert-butylcarbamoyl-2-phenyl-ethyl)-formyl-amino]-4,5-bis-(2,2-dimethyl-propionyloxy)-tetrahydro-pyran-3-yl ester (126402-91-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 89 percent / pyridine / 24 h / Ambient temperature

2: 88 percent / H₂ / Raney Ni / methanol; CH₂Cl₂ / 3 h / 760 Torr / Ambient temperature

3: ZnCl₂ / tetrahydrofuran / 24 h / -78 °C

With pyridine; hydrogen; zinc(II) chloride; nickel; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1055/s-1991-26641

Downstream raw materials:

2,2-Dimethyl-propionic acid (2S,3S,4R,5R)-2-[((R)-1-tert-butylcarbamoyl-2-phenyl-ethyl)-formyl-amino]-4,5-bis-(2,2-dimethyl-propionyloxy)-tetrahydro-pyran-3-yl ester

2,2-Dimethyl-propionic acid (2S,3S,4R,5R)-2-{[(S)-tert-butylcarbamoyl-(4-chloro-phenyl)-methyl]-formyl-amino}-4,5-bis-(2,2-dimethyl-propionyloxy)-tetrahydro-pyran-3-yl ester

N-(4-Chlorobenzylidene)-2,3,4-tri-O-pivaloyl-α-D-arabinopyranosylamine

N-Benzylidene-2,3,4-tri-O-pivaloyl-α-D-arabinopyranosylamine

Refernces