1-chloro-N-phenylcyclohexanecarboxamide

Base Information

• Chemical Name: 1-chloro-N-phenylcyclohexanecarboxamide
• CAS No.: 4664-73-7
• Molecular Formula: C13H16 Cl N O
• Molecular Weight: 237.729
• Mol file: 4664-73-7.mol

Synonyms:Cyclohexanecarboxanilide,1-chloro- (7CI,8CI); NSC 289475

Chemical Property of 1-chloro-N-phenylcyclohexanecarboxamide

Chemical Property:

• Vapor Pressure: 3.7E-07mmHg at 25°C
• Boiling Point: 416.9°C at 760 mmHg
• Flash Point: 205.9°C
• Density: 1.17g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-chloro-N-phenylcyclohexanecarboxamide

There total 4 articles about 1-chloro-N-phenylcyclohexanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

1-bromo-N-phenylcyclohexane-1-carboxamide → 1-Chlor-cyclohexan-1-carbonsaeure-anilid (4664-73-7)

Guidance literature:

With hexaaquocopper(II) tetrafluoroborate; dichloromethane; N,N,N',N'',N'''-pentamethyldiethylenetriamine; at 100 ℃; for 1h; Inert atmosphere;

DOI:10.1246/cl.170062

Reference yield:

N-phenylcyclohexanamide (2719-26-8) → 1-Chlor-cyclohexan-1-carbonsaeure-anilid (4664-73-7)

Guidance literature:

Multistep reaction; (i) PCl₅, benzene, (ii) H₂O;

DOI:10.1021/jo01023a002

Reference yield:

aniline (62-53-3) → 1-Chlor-cyclohexan-1-carbonsaeure-anilid (4664-73-7)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) SOCl₂, (ii) /BRN= 605631/, benzene

2: (i) PCl₅, benzene, (ii) H₂O

DOI:10.1021/jo01023a002

upstream raw materials:

N-phenylcyclohexanamide

aniline

Cyclohexanecarboxylic acid

Refernces