2'-F-dU Phosphoramidite

Base Information Edit

Chemical Name:2'-F-dU Phosphoramidite
CAS No.:146954-75-8
Molecular Formula:C₃₉H₄₆FN₄O₈P
Molecular Weight:748.788
Hs Code.:
European Community (EC) Number:890-263-5
DSSTox Substance ID:DTXSID10430990
Mol file:146954-75-8.mol

Synonyms:2'-F-dU Phosphoramidite;146954-75-8;DMT-2'Fluoro-dU Phosphoramidite;3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-fluorooxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile;DMT-2 inverted exclamation markaFluoro-dU Phosphoramidite;5/'-O-(4,4-Dimethoxytrityl)-2/'-deoxy-2/'-fluorouridine-3/'-(2-cyanoethyl-N,N-diisopropyl)phosphoram;DMT-2'Fluoro-dU Phosphoramidite, configured for ABI;C39H46FN4O8P;2'-F-dUPhosphoramidite;2/'-F-Du Phosphoramidite;(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite;SCHEMBL1598782;DTXSID10430990;DMT-2'-Fluoro-dU Phosphoramidite;5'-O-(4,4-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;MFCD11113919;AC-32387;BP-28844;HY-45409;PD157954;CS-0147075;D5941;C72792;5'-O-DMT-2'-F-Deoxyuridine-CE Phosphoramidit;W-201303;DMT-2'Fluoro-dU Phosphoramidite, configured for MerMade;2'-Deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-fluorouridine 3-CE phosphoramidite;DMT-2'Fluoro-dU Phosphoramidite, configured for (??KTA(R) and OligoPilot(R));3-[({[(2R,3R,4R,5R)-2-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluorooxolan-3-yl]oxy}[bis(propan-2-yl)amino]phosphanyl)oxy]propanenitrile;5'-O-(4,4'-Dimethoxytrityl)-2'-fluoro-2'-deoxyuridine-3'-(2-cyanoethyl diisopropylphosphoramidite)

Suppliers and Price of 2'-F-dU Phosphoramidite

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2''-F-dUPhosphoramidite
250mg
$ 90.00

Sigma-Aldrich
DMT-2′Fluoro-dU Phosphoramidite ≥99% (31P-NMR)
500g
$ 27270.00

Sigma-Aldrich
DMT-2′Fluoro-dU Phosphoramidite ≥99% (31P-NMR)
100g
$ 6100.00

Sigma-Aldrich
DMT-2′Fluoro-dU Phosphoramidite configured for (KTA
5g
$ 795.00

Sigma-Aldrich
DMT-2′Fluoro-dU Phosphoramidite configured for PerkinElmer, configured for Polygen
0.25g
$ 47.20

Sigma-Aldrich
DMT-2′Fluoro-dU Phosphoramidite configured for ABI
0.25g
$ 47.20

Sigma-Aldrich
DMT-2′Fluoro-dU Phosphoramidite configured for ABI
1g
$ 124.00

Sigma-Aldrich
DMT-2′Fluoro-dU Phosphoramidite configured for PerkinElmer, configured for Polygen
2g
$ 285.00

Crysdot
2'-F-dUPhosphoramidite 95+%
5g
$ 446.00

Chemenu
(2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl(2-cyanoethyl)diisopropylphosphoramidite 95%
5g
$ 421.00

Total 43 raw suppliers

Chemical Property of 2'-F-dU Phosphoramidite Edit

Chemical Property:

PKA:9.39±0.10(Predicted)
PSA：150.86000
LogP:6.45918
Storage Temp.:?20°C
XLogP3:5.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:17
Exact Mass:748.30372960
Heavy Atom Count:53
Complexity:1230

Purity/Quality:

98% ^*data from raw suppliers

2''-F-dUPhosphoramidite ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1F)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
Isomeric SMILES:CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1F)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

Technology Process of 2'-F-dU Phosphoramidite

There total 7 articles about 2'-F-dU Phosphoramidite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%