Cyclohexaneacetaldehyde-formyl-d, 2-acetyl-, trans- (9CI)

Base Information

• Chemical Name: Cyclohexaneacetaldehyde-formyl-d, 2-acetyl-, trans- (9CI)
• CAS No.: 152090-48-7
• Molecular Formula: C₁₀H₁₆O₂
• Molecular Weight: 168.236
• Mol file: 152090-48-7.mol

Synonyms:Cyclohexaneacetaldehyde-formyl-d,2-acetyl-, trans- (9CI); Cyclohexaneacetaldehyde-formyl-d, 2-acetyl-, trans-(?à)-

Chemical Property of Cyclohexaneacetaldehyde-formyl-d, 2-acetyl-, trans- (9CI)

Chemical Property:

• Boiling Point: 269.0±13.0 °C(Predicted)
• PSA: 34.14000
• Density: 0.974±0.06 g/cm3(Predicted)
• LogP: 1.97080

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclohexaneacetaldehyde-formyl-d, 2-acetyl-, trans- (9CI)

There total 9 articles about Cyclohexaneacetaldehyde-formyl-d, 2-acetyl-, trans- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4aS,8bR)-2,2,8b-Trimethyl-octahydro-1,3-dioxa-biphenylen-4-one (137277-93-1) → (2-Acetyl-cyclohexyl)-acetaldehyde (152090-48-7)

Guidance literature:

With diisobutylaluminium hydride; In hexane; at -60 ℃; for 1h; Yield given;

DOI:10.1021/ja00530a059

Reference yield:

1-Acetyl-2-(2-propenyl)cyclohexane (36306-62-4) → (2-Acetyl-cyclohexyl)-acetaldehyde (152090-48-7)

Guidance literature:

1-Acetyl-2-(2-propenyl)cyclohexane; With ozone; In dichloromethane; at -78 ℃; for 0.0833333h; Inert atmosphere;

With triphenylphosphine; In dichloromethane; at 23 ℃; Inert atmosphere;

DOI:10.1021/acs.joc.6b01370

Reference yield:

C13H20O3 → (2-Acetyl-cyclohexyl)-acetaldehyde (152090-48-7)

Guidance literature:

With diisobutylaluminium hydride; In toluene; at -60 ℃;

DOI:10.1055/s-0036-1589465

upstream raw materials:

(4aS,8bR)-2,2,8b-Trimethyl-octahydro-1,3-dioxa-biphenylen-4-one

1-cyclohexenyl methyl ketone

1-Acetyl-2-(2-propenyl)cyclohexane

Refernces

• 1、 Molander, Gary A.,Cameron, Kimberly O.. "Neighboring Group Participation in Lewis Acid-Promoted and Annulations. The Stereocontrolled Synthesis of Tricyclic Ethers". . p. 5931 - 5943. Retrieved 2007/10/02.
• 2、 Schreiber, Stuart L.. "Fragmentation Reactions of α-Alkoxy Hydroperoxides and Application to the Synthesis of the Macrolide (+/-)-Recifeiolide". . p. 6163 - 6165. Retrieved 2007/10/02.