N-[1-(furan-2-yl)ethylidene]hydroxylamine

Base Information

• Chemical Name: N-[1-(furan-2-yl)ethylidene]hydroxylamine
• CAS No.: 5007-50-1
• Molecular Formula: C6H7NO2
• Molecular Weight: 125.127
• Hs Code.: 2932190090
• European Community (EC) Number: 637-121-9
• Mol file: 5007-50-1.mol

Synonyms:N-[1-(furan-2-yl)ethylidene]hydroxylamine;2-ACETYLFURAN OXIME;methyl furyl ketoxime;SCHEMBL2906532;HMS2202N19;(E)-1-(furan-2-yl)ethanone oxime;AKOS017263175;FT-0694260

Chemical Property of N-[1-(furan-2-yl)ethylidene]hydroxylamine

Chemical Property:

• Vapor Pressure: 0.0716mmHg at 25°C
• Melting Point: 104 °C
• Refractive Index: 1.518
• Boiling Point: 218.8 °C at 760 mmHg
• Flash Point: 86.1 °C
• PSA: 45.73000
• Density: 1.15 g/cm³
• LogP: 1.47780
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 125.047678466
• Heavy Atom Count: 9
• Complexity: 122

Purity/Quality:

98%min ^*data from raw suppliers

1-(2-Furyl)-1-ethanone oxime 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NO)C1=CC=CO1

Technology Process of N-[1-(furan-2-yl)ethylidene]hydroxylamine

There total 3 articles about N-[1-(furan-2-yl)ethylidene]hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-(2-furyl)-1-ethanone (1192-62-7,80145-44-4) → 1-(2-furyl)ethanone oxime (5007-50-1)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In ethanol; water; Reflux;

DOI:10.1021/acs.orglett.5b03462

Reference yield:

N'-(1-(furan-2-yl)ethylidene)-4-methylbenzenesulfonohydrazide (68727-98-0) → 1-(2-furyl)ethanone oxime (5007-50-1)

Guidance literature:

With sodium hydroxide; In nitromethane; dimethyl sulfoxide; at 110 ℃; for 16h; Schlenk technique;

DOI:10.1016/j.tet.2013.03.055

Reference yield:

→ 1-(2-furyl)ethanone oxime (5007-50-1)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; In ethanol; for 4h; Reflux;

upstream raw materials:

1-(2-furyl)-1-ethanone

N'-(1-(furan-2-yl)ethylidene)-4-methylbenzenesulfonohydrazide

Downstream raw materials:

1-(2-furyl)-1-ethanone

1-(furan-2-yl)ethanamine

N-(furan-2-yl)acetamide

Refernces

• 1、 Liu, Rui-Hua,Shen, Zhen-Yao,Wang, Cong,Loh, Teck-Peng,Hu, Xu-Hong. "Selective Dehydrogenative Acylation of Enamides with Aldehydes Leading to Valuable β-Ketoenamides". supporting information. p. 944 - 949. Retrieved 2020/02/15.
• 2、 Miao, Chun-Bao,Zheng, An-Qi,Zhou, Li-Jin,Lyu, Xinyu,Yang, Hai-Tao. "Copper-Catalyzed Annulation of Oxime Acetates with α-Amino Acid Ester Derivatives: Synthesis of 3-Sulfonamido/Imino 4-Pyrrolin-2-ones". supporting information. p. 3381 - 3385. Retrieved 2020/04/21.