METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE

Base Information

• Chemical Name: METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE
• CAS No.: 51718-80-0
• Molecular Formula: C6H9ClN2O2
• Molecular Weight: 176.603
• Hs Code.: 2933290090
• Mol file: 51718-80-0.mol

Synonyms:METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE

Chemical Property of METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE

Chemical Property:

• PSA: 54.98000
• LogP: 0.92720
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%Min ^*data from raw suppliers

Methyl2-(1H-Imidazol-4-yl)acetateHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Methyl 2-(1H-Imidazol-4-yl)acetate Hydrochloride is used in the analysis of potent non-?thiol inhibitors of farnesyl protein transferase.

Technology Process of METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE

There total 6 articles about METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + imidazole-4-acetic acid hydrochloride (3251-69-2) → methyl 2-(1H-imidazol-4-yl)acetate hydrochloride (51718-80-0)

Guidance literature:

With hydrogenchloride; at 20 ℃; for 5.5h;

Reference yield: 98.0%

methanol (67-56-1) + 2-(1H-imidazol-4-yl)acetic acid (645-65-8) → methyl 2-(1H-imidazol-4-yl)acetate hydrochloride (51718-80-0)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 60 ℃;

Reference yield:

imidazole-4-acetic acid hydrochloride (3251-69-2) → methyl 2-(1H-imidazol-4-yl)acetate hydrochloride (51718-80-0)

Guidance literature:

With trimethyl orthoformate; In methanol;

upstream raw materials:

methanol

imidazole-4-acetic acid hydrochloride

2-(1H-imidazol-4-yl)acetic acid

Downstream raw materials:

methyl {1-[(4-methylphenyl)sulfonyl]-1H-imidazol-4-yl}acetate

1-(4-Nitrophenylmethyl)-1H-imidazol-4-ylacetic acid methyl ester

N,N'-(5,5'-((1S,3S)-cyclohexane-1,3-diyl)bis(1,3,4-thiadiazole-5,2-diyl))bis(2-(1H-imidazol-4-yl)acetamide)

Refernces

• 1、 -. "COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES AS GLUTAMINASE INHIBITORS FOR TREATING CANCERS THEREOF". Page/Page column 186. . Retrieved 2014/06/11.
• 2、 -. "COMPOUNDS AND THEIR METHODS OF USE". Paragraph 0895-0897. . Retrieved 2014/05/25.