Pyridine-2,3,4-triamine

Base Information

• Chemical Name: Pyridine-2,3,4-triamine
• CAS No.: 52559-11-2
• Molecular Formula: C5H8N4
• Molecular Weight: 124.145
• Hs Code.: 2933399990
• Mol file: 52559-11-2.mol

Synonyms:Pyridine-2,3,4-triamine

Chemical Property of Pyridine-2,3,4-triamine

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 253 °C
• Refractive Index: 1.766
• Boiling Point: 433.166ºC at 760 mmHg
• PKA: 9.38±0.47(Predicted)
• Flash Point: 245.712ºC
• PSA: 90.95000
• Density: 1.387g/cm3
• LogP: 1.57180
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Pyridine-2,3,4-triamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyridine-2,3,4-triamine

There total 10 articles about Pyridine-2,3,4-triamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,4-dibenzylamino-3-nitro-pyridine (1047619-53-3) → 2,3,4-pyridinetriamine (52559-11-2)

Guidance literature:

With hydrogen; acetic acid; palladium on activated charcoal;

Reference yield:

2,4-dihydroxy-3-nitropyridine (89282-12-2) → 2,3,4-pyridinetriamine (52559-11-2)

Guidance literature:

Multi-step reaction with 3 steps

1: phosphoryl chloride

2: ethanolic NH₃ / 100 °C

3: Na₂S; H₂O

With sodium sulfide; ammonia; water; trichlorophosphate;

Reference yield:

2,4-dichloro-3-nitro-pyridine (5975-12-2) → 2,3,4-pyridinetriamine (52559-11-2)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanolic NH₃ / 100 °C

2: Na₂S; H₂O

With sodium sulfide; ammonia; water;

upstream raw materials:

2,4-diamino-3-nitropyridine

3-deazauracil

4,6-dihydroxy-nicotinic acid

4,6-dihydroxynicotinic acid ethyl ester

Downstream raw materials:

pyrido[3,4-b]pyrazin-5-amine

2-(4-Nitro-phenyl)-3H-imidazo[4,5-c]pyridine-6-ylamine

3-(2,4-diamino-pyridin-3-ylamino)-5,5-dimethyl-cyclohex-2-enone

4-amino-10-(4-benzyloxy-2-fluoro-phenyl)-7,7-dimethyl-5,6,7,8,10,11-hexahydro-benzo[e]pyrido[2,3-b][1,4]diazepin-9-one

Refernces

• 1、 -. "Diaminopyridine compounds and methods of use". . . Retrieved 2008/06/13.