9H-Xanthene-9-methanol

Base Information

• Chemical Name: 9H-Xanthene-9-methanol
• CAS No.: 5490-92-6
• Molecular Formula: C14H12O2
• Molecular Weight: 212.248
• Hs Code.: 2932999099
• DSSTox Substance ID: DTXSID90384280
• Nikkaji Number: J1.585.171F
• Wikidata: Q82176295
• Mol file: 5490-92-6.mol

Synonyms:9H-Xanthene-9-methanol;(9H-xanthen-9-yl)methanol;5490-92-6;9H-xanthen-9-ylmethanol;9-xanthenemethanol;9-hydroxymethylxanthene;Maybridge3_000515;Oprea1_124438;SCHEMBL8820720;DTXSID90384280;XODHGYGQZLHGJZ-UHFFFAOYSA-N;HMS1432H09;CS-M0134;AKOS015156486;CCG-233810;IDI1_011902;AC-12965;CS-13507;FT-0730509;EN300-1708909

Chemical Property of 9H-Xanthene-9-methanol

Chemical Property:

• Vapor Pressure: 3.95E-05mmHg at 25°C
• Melting Point: 67-68 °C(Solv: ligroine (8032-32-4))
• Refractive Index: 1.618
• Boiling Point: 338 °C at 760 mmHg
• PKA: 13.07±0.10(Predicted)
• Flash Point: 151.1 °C
• PSA: 29.46000
• Density: 1.208g/cm³
• LogP: 2.91650
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 212.083729621
• Heavy Atom Count: 16
• Complexity: 219

Purity/Quality:

NLT 98% ^*data from raw suppliers

(9H-xanthen-9-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C3O2)CO

Technology Process of 9H-Xanthene-9-methanol

There total 4 articles about 9H-Xanthene-9-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

xanthene-9-carboxylic acid (82-07-5) → xanthene-9-methanol (5490-92-6)

Guidance literature:

With lithium aluminium tetrahydride; In water; at 20 ℃; for 1h; Reflux; Inert atmosphere;

DOI:10.1039/c7ra08608c

Reference yield:

F-ether + xanthene-9-carboxylic acid (82-07-5) → xanthene-9-methanol (5490-92-6)

Guidance literature:

In tetrahydrofuran; methanol; water;

Reference yield:

9H-xanthene-9-carboxylic acid methyl ester (39497-06-8) → xanthene-9-methanol (5490-92-6)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

DOI:10.1139/v57-147

upstream raw materials:

xanthene-9-carboxylic acid

9H-xanthene-9-carboxylic acid methyl ester

Downstream raw materials:

benzoic acid xanthen-9-ylmethyl ester

xanthene

9-iodomethyl-9H-xanthene

9-xanthylmethyl p-nitrophenylcarbonate

Refernces

• 1、 Kustra,Martin,Chateau,Lerouge,Monnereau,Andraud,Sitarz,Baldeck,Parola. "Two-photon controlled sol-gel condensation for the microfabrication of silica based microstructures. the role of photoacids and photobases". . p. 46615 - 46620. Retrieved 2017/10/16.
• 2、 Du, Hong,Boyd, Mary K. "The 9-xanthenylmethyl group: A novel photocleavable protecting group for amines". . p. 6645 - 6647. Retrieved 2007/10/03.