NALPHA,NOMEGA-DICARBOBENZOXY-L-ARGININE

Base Information

• Chemical Name: NALPHA,NOMEGA-DICARBOBENZOXY-L-ARGININE
• CAS No.: 53934-75-1
• Molecular Formula: C22H26N4O6
• Molecular Weight: 442.47
• Mol file: 53934-75-1.mol

Synonyms:NALPHA,NOMEGA-DICARBOBENZOXY-L-ARGININE;NALPHA,NOMEGA-DI-CBZ-L-ARGININE;Dicarbobenzoxyarginine;Nalpha,nomega-Dicarbobenzoyl-L-arginine;alpha,omega-Di-Z-Arg-OH

Chemical Property of NALPHA,NOMEGA-DICARBOBENZOXY-L-ARGININE

Chemical Property:

• Melting Point: 150 °C
• Refractive Index: 1.593
• PKA: 3.91±0.21(Predicted)
• PSA: 149.84000
• Density: 1.29±0.1 g/cm3(Predicted)
• LogP: 3.86940
• Solubility.: almost transparency in Pyridine

Purity/Quality:

98%,99%, ^*data from raw suppliers

Nα,Nω-Di-Cbz-L-arginine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Nα,Nω-Di-Cbz-L-arginine can be used microbial control agent for food preservation.

Technology Process of NALPHA,NOMEGA-DICARBOBENZOXY-L-ARGININE

There total 2 articles about NALPHA,NOMEGA-DICARBOBENZOXY-L-ARGININE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-arginine (74-79-3,25212-18-4) + benzyl chloroformate (501-53-1,94274-21-2) → Nα,Nγ-bis(benzyloxycarbonyl)-L-arginine (53934-75-1)

Guidance literature:

With sodium hydroxide; In water; at 0 ℃;

Reference yield:

L-arginine (74-79-3,25212-18-4) → Nα,Nγ-bis(benzyloxycarbonyl)-L-arginine (53934-75-1)

Guidance literature:

With benzyl chloroformate;

DOI:10.1021/jo01362a052

Reference yield:

1-bromo dodecane (112-29-8) + Nα,Nγ-bis(benzyloxycarbonyl)-L-arginine (53934-75-1) → Nα,Nγ-bis(benzyloxycarbonyl)-L-arginine decyl ester

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 36h;

upstream raw materials:

L-arginine

benzyl chloroformate

Downstream raw materials:

H-Arg(Z)-OH

N^ω-benzyloxycarbonyl-L-arginine methyl ester

Arg-OBzl

((S)-3-benzyloxycarbonylamino-2-oxo-piperidine-1-carboximidoyl)-carbamic acid benzyl ester

Refernces