4-(2-(N-Acetylamino)ethyl)benzoicacid

Base Information

• Chemical Name: 4-(2-(N-Acetylamino)ethyl)benzoicacid
• CAS No.: 7465-13-6
• Molecular Formula: C11H13 N O3
• Molecular Weight: 207.23
• Hs Code.: 2924299090
• Mol file: 7465-13-6.mol

Synonyms:Benzoicacid, p-(2-acetamidoethyl)- (8CI); 4-(2-Acetamidoethyl)benzoic acid;4-(2-Acetylaminoethyl)benzoic acid; NSC 400161

Chemical Property of 4-(2-(N-Acetylamino)ethyl)benzoicacid

Chemical Property:

• Vapor Pressure: 8.93E-10mmHg at 25°C
• Boiling Point: 473.6°C at 760 mmHg
• Flash Point: 240.2°C
• PSA: 66.40000
• LogP: 1.45430

Purity/Quality:

99% ^*data from raw suppliers

4-(2-acetamidoethyl)benzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(2-(N-Acetylamino)ethyl)benzoicacid

There total 4 articles about 4-(2-(N-Acetylamino)ethyl)benzoicacid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 4-(2-acetamidoethyl)benzoate (870703-69-8) → 4-(2-acetamidoethyl)benzoic acid (7465-13-6)

Guidance literature:

With lithium hydroxide monohydrate; water; In tetrahydrofuran; methanol; at 25 ℃; for 16h;

Reference yield:

N-[2-(4-acetylphenyl)ethyl]acetamide (23279-64-3) → 4-(2-acetamidoethyl)benzoic acid (7465-13-6)

Guidance literature:

With 1,4-dioxane; alkaline aqueous sodium hypobromite;

DOI:10.1021/ja01252a036

Reference yield:

methyl-N-(benzyl-methyl)-formamide (877-95-2) → 4-(2-acetamidoethyl)benzoic acid (7465-13-6)

Guidance literature:

Multi-step reaction with 2 steps

1: aluminium chloride; 1.1.2.2-tetrachloro-ethane

2: dioxane; alkaline aqueous sodium hypobromite

With 1,4-dioxane; aluminium trichloride; alkaline aqueous sodium hypobromite; 1,1,2,2-tetrachloroethane;

DOI:10.1021/ja01252a036

upstream raw materials:

N-[2-(4-acetylphenyl)ethyl]acetamide

methyl-N-(benzyl-methyl)-formamide

methyl 4-(2-acetamidoethyl)benzoate

4-(2-amino-ethyl)-benzoic acid methyl ester

Downstream raw materials:

3-{4-[2-(2-Phenoxy-acetylamino)-ethyl]-phenyl}-propionic acid

β-[4-(2-acetamidoethyl)-phenyl]-propionic acid

4-(2-Acetamido-ethyl)-zimtsaeure

acetic acid-N-(2-<4-hydroxymethylphenyl>-ethyl)-amide

Refernces