1-Methoxy-3-vinylbenzene

Base Information

• Chemical Name: 1-Methoxy-3-vinylbenzene
• CAS No.: 626-20-0
• Molecular Formula: C9H10O
• Molecular Weight: 134.178
• Hs Code.: 2909309090
• DSSTox Substance ID: DTXSID90342749
• Nikkaji Number: J43.390J
• Wikidata: Q82113705
• Mol file: 626-20-0.mol

Synonyms:1-Methoxy-3-vinylbenzene;626-20-0;3-Vinylanisole;1-ethenyl-3-methoxybenzene;3-methoxystyrene;Benzene, 1-ethenyl-3-methoxy-;m-vinylanisole;m-methoxystyrene;3-vinyl-anisole;3-Vinylanisole, 97%;1-Methoxy-3-vinylbenzene #;3-VINYLANISOLE 97;SCHEMBL145874;SCHEMBL13341237;DTXSID90342749;MFCD03427262;AKOS009827327;AMY202100110;AS-40403;CS-0204765;A937108;3-Vinylanisole (3-Methoxystyrene), stabilized with 4-t-Butylcatechol

Chemical Property of 1-Methoxy-3-vinylbenzene

Chemical Property:

• Refractive Index: n20/D 1.5540(lit.)
• Boiling Point: 202.5 °C at 760 mmHg
• Flash Point: 72.5 °C
• PSA: 9.23000
• Density: 0.962 g/cm³
• LogP: 2.33820
• Storage Temp.: 2-8°C
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 134.073164938
• Heavy Atom Count: 10
• Complexity: 109

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Vinylanisole 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC1=CC=CC(=C1)C=C

Technology Process of 1-Methoxy-3-vinylbenzene

There total 46 articles about 1-Methoxy-3-vinylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3-methoxy-1-iodobenzene (766-85-8) + vinyl magnesium bromide (1826-67-1) → 3-methoxystyrene (626-20-0)

Guidance literature:

vinyl magnesium bromide; With gallium(III) trichloride; In tetrahydrofuran; hexane; dimethyl sulfoxide; at 25 ℃;

3-methoxy-1-iodobenzene; With tris-(o-tolyl)phosphine; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran; hexane; dimethyl sulfoxide; Heating;

DOI:10.1055/s-2002-32608

Reference yield: 97.0%

Triethoxyvinylsilane (78-08-0) + 3-methoxy-1-iodobenzene (766-85-8) → 3-methoxystyrene (626-20-0)

Guidance literature:

With sodium hydroxide; In methanol; water; at 100 ℃; for 5h; Sealed tube;

DOI:10.1002/ejoc.201400162

Reference yield: 95.0%

Methyltriphenylphosphonium bromide (1779-49-3) + 3-methoxy-benzaldehyde (591-31-1) → 3-methoxystyrene (626-20-0)

Guidance literature:

With potassium carbonate; In tetrahydrofuran; Inert atmosphere; Reflux;

DOI:10.1021/ol5029892

upstream raw materials:

2-(3-methoxyphenyl)-ethanol

trans-3-methoxycinnamic acid

3-hydroxystyrene

dimethyl sulfate

Downstream raw materials:

3-ethylanisole

1-(1,2-dibromoethyl)-3-methoxybenzene

4-(3-methoxy-phenyl)-azetidin-2-one

(E)-3-(3-methoxyphenyl)acrylamide

Refernces

• 1、 Su, Mincong,Huang, Xia,Lei, Chuanhu,Jin, Jian. "Nickel-Catalyzed Reductive Cross-Coupling of Aryl Bromides with Vinyl Acetate in Dimethyl Isosorbide as a Sustainable Solvent". supporting information. p. 354 - 358. Retrieved 2022/01/15.
• 2、 -. "COMPOUNDS AND USES THEREOF". Page/Page column 174-175. . Retrieved 2021/08/06.