3,3,4,4,5,5,5-HEPTAFLUOROPENTANOIC ACID

Base Information

• Chemical Name: 3,3,4,4,5,5,5-HEPTAFLUOROPENTANOIC ACID
• CAS No.: 679-46-9
• Molecular Formula: C5H3F7O2
• Molecular Weight: 228.06
• Mol file: 679-46-9.mol

Synonyms:RARECHEM AL BE 0962;3,3,4,4,5,5,5-HEPTAFLUOROPENTANOIC ACID

Chemical Property of 3,3,4,4,5,5,5-HEPTAFLUOROPENTANOIC ACID

Chemical Property:

• PSA: 37.30000
• LogP: 2.29400

Purity/Quality:

99%min ^*data from raw suppliers

3,3,4,4,5,5,5-HEPTAFLUOROPENTANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,3,4,4,5,5,5-HEPTAFLUOROPENTANOIC ACID

There total 4 articles about 3,3,4,4,5,5,5-HEPTAFLUOROPENTANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

3,3,4,4,5,5,6,6,6-nonafluorohexan-1-ol (755-40-8) → 3,3,4,4,5,5,5-heptafluoropentanoic acid (679-46-9)

Guidance literature:

With Jones reagent; In diethyl ether; acetone; at 0 ℃; for 2h;

DOI:10.1021/jacs.5b11064

Reference yield:

1,1,1,2,2,3,3,5,5-nonafluoro-5-iodo-pentane (755-46-4) → 3,3,4,4,5,5,5-heptafluoropentanoic acid (679-46-9)

Guidance literature:

With silver(I) nitrite; In N,N-dimethyl-formamide;

DOI:10.1021/ja01496a049

Reference yield:

5,5,5,4,4,3,3-heptafluoro-n-pentyl iodide (1513-88-8,71215-70-8) → 3,3,4,4,5,5,5-heptafluoropentanoic acid (679-46-9)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid

2: potassium hydroxide; diethylene glycol

3: acetone; chromium (VI)-oxide; sulfuric acid

With chromium(VI) oxide; potassium hydroxide; sulfuric acid; acetic acid; acetone; diethylene glycol;

DOI:10.1016/S0010-440X(00)80017-6

upstream raw materials:

3,3,4,4,5,5,6,6,6-nonafluorohexan-1-ol

1,1,1,2,2,3,3,5,5-nonafluoro-5-iodo-pentane

5,5,5,4,4,3,3-heptafluoro-n-pentyl iodide

acetic acid-(3,3,4,4,5,5,5-heptafluoro-pentyl ester)

Refernces