Technology Process of 3-Bromo-4-cyano-2-hydroxy-1-aminobenzene
There total 3 articles about 3-Bromo-4-cyano-2-hydroxy-1-aminobenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ethanol; tin(ll) chloride;
at 20 ℃;
for 16h;
DOI:10.1021/jm034248l
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 30 percent / hexamethylene tetramine; hydrogen tribromide / CH2Cl2 / 72 h / 25 °C
2: 85 percent / SnCl2; ethanol / 16 h / 20 °C
With
hydrogene tribromide; ethanol; hexamethylenetetramine; tin(ll) chloride;
In
dichloromethane;
DOI:10.1021/jm034248l
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 22 percent / sodium nitrate; aq. sulfuric acid; NaNO2 / CH2Cl2 / 16 h / 25 °C
2: 30 percent / hexamethylene tetramine; hydrogen tribromide / CH2Cl2 / 72 h / 25 °C
3: 85 percent / SnCl2; ethanol / 16 h / 20 °C
With
sodium nitrate; hydrogene tribromide; ethanol; hexamethylenetetramine; sulfuric acid; tin(ll) chloride; sodium nitrite;
In
dichloromethane;
DOI:10.1021/jm034248l