Thiazole-2-carbothioic acid amide

Base Information

• Chemical Name: Thiazole-2-carbothioic acid amide
• CAS No.: 60758-41-0
• Molecular Formula: C4H4N2S2
• Molecular Weight: 144.221
• Hs Code.: 2934100090
• European Community (EC) Number: 832-835-9
• ChEMBL ID: CHEMBL4545405
• DSSTox Substance ID: DTXSID90569434
• Wikidata: Q72508234
• Mol file: 60758-41-0.mol

Synonyms:60758-41-0;THIAZOLE-2-CARBOTHIOIC ACID AMIDE;THIAZOLE-2-CARBOTHIOAMIDE;1,3-thiazole-2-carbothioamide;1,3-THIAZOLE-2-THIOCARBOXAMIDE;MFCD06738992;2-thiazol carbothioamide;SCHEMBL1314765;CHEMBL4545405;DTXSID90569434;AKOS005256880;THIAZOLE-2-CARBOTHIOICACIDAMIDE;AB28335;AT14697;SY262109;CS-0224151;EN300-1179895;A832871

Chemical Property of Thiazole-2-carbothioic acid amide

Chemical Property:

• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.718
• Boiling Point: 284℃
• Flash Point: 125℃
• PSA: 99.24000
• Density: 1.461
• LogP: 1.47760
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 143.98159048
• Heavy Atom Count: 8
• Complexity: 104

Purity/Quality:

97% ^*data from raw suppliers

Thiazole-2-carbothioicAcidAmide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CSC(=N1)C(=S)N

Technology Process of Thiazole-2-carbothioic acid amide

There total 1 articles about Thiazole-2-carbothioic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiazole-2-carbonitrile (1452-16-0) → thiazole-2-carbothioamide (60758-41-0)

Guidance literature:

With ethanol; hydrogen sulfide; ammonia;

DOI:10.1039/jr9560002253

Reference yield: 70.0%

thiazole-2-carbothioamide (60758-41-0) + 2-(methoxyphenylmethylene)malononitrile (42754-56-3) → 4-phenyl-2-(thiazol-2-yl)-6-thioxo-1,6-dihydropyrimidine-5-carbonitrile

Guidance literature:

With sodium isopropylate; In isopropyl alcohol; at 20 ℃; for 5h;

Reference yield:

thiazole-2-carbothioamide (60758-41-0) → Thiazol-carbonsaeure-(2)-amidhydrazon (90980-72-6)

Guidance literature:

With hydrazine hydrate; In ethanol; hexane;

upstream raw materials:

thiazole-2-carbonitrile

Downstream raw materials:

Thiazol-carbonsaeure-(2)-amidhydrazon