[(3~{S},4~{S})-3-methoxyoxan-4-yl]-[(1~{R},3~{S})-3-propan-2-yl-3-[[3-(trifluoromethyl)-7,8-dihydro-5~{H}-1,6-naphthyridin-6-yl]carbonyl]cyclopentyl]azanium

Base Information Edit

Chemical Name:[(3~{S},4~{S})-3-methoxyoxan-4-yl]-[(1~{R},3~{S})-3-propan-2-yl-3-[[3-(trifluoromethyl)-7,8-dihydro-5~{H}-1,6-naphthyridin-6-yl]carbonyl]cyclopentyl]azanium
CAS No.:624733-88-6
Molecular Formula:C24H34F3N3O3
Molecular Weight:469.547
Hs Code.:
DSSTox Substance ID:DTXSID9047336
Wikidata:Q72492508
Mol file:624733-88-6.mol

Synonyms:[(3~{S},4~{S})-3-methoxyoxan-4-yl]-[(1~{R},3~{S})-3-propan-2-yl-3-[[3-(trifluoromethyl)-7,8-dihydro-5~{H}-1,6-naphthyridin-6-yl]carbonyl]cyclopentyl]azanium;F7N;DTXSID9047336;NCGC00248371-01;1,5-anhydro-2,3-dideoxy-4-O-methyl-3-{[(1R,3S)-3-(propan-2-yl)-3-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopentyl]ammonio}-D-erythro-pentitol

Suppliers and Price of [(3~{S},4~{S})-3-methoxyoxan-4-yl]-[(1~{R},3~{S})-3-propan-2-yl-3-[[3-(trifluoromethyl)-7,8-dihydro-5~{H}-1,6-naphthyridin-6-yl]carbonyl]cyclopentyl]azanium

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
MK 0812
1mg
$ 305.00

TRC
MK0812
10mg
$ 165.00

DC Chemicals
MK0812 >98%
1 g
$ 3000.00

Crysdot
MK0812 98+%
10mg
$ 326.00

Crysdot
MK0812 98+%
5mg
$ 182.00

Cayman Chemical
MK-0812 ≥98%
10mg
$ 480.00

Cayman Chemical
MK-0812 ≥98%
5mg
$ 256.00

Cayman Chemical
MK-0812 ≥98%
1mg
$ 64.00

Biosynth Carbosynth
MK 0812
10 mg
$ 145.00

Biosynth Carbosynth
MK 0812
50 mg
$ 507.50

Total 30 raw suppliers

Chemical Property of [(3~{S},4~{S})-3-methoxyoxan-4-yl]-[(1~{R},3~{S})-3-propan-2-yl-3-[[3-(trifluoromethyl)-7,8-dihydro-5~{H}-1,6-naphthyridin-6-yl]carbonyl]cyclopentyl]azanium Edit

Chemical Property:

Boiling Point:562 °C at 760 mmHg
PKA:8.51±0.40(Predicted)
Flash Point:293.7 °C
PSA：63.69000
Density:1.24 g/cm³
LogP:3.90230
Solubility.:Soluble in DMSO
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:470.26305147
Heavy Atom Count:33
Complexity:692

Purity/Quality:

98% min ^*data from raw suppliers

MK 0812 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1(CCC(C1)[NH2+]C2CCOCC2OC)C(=O)N3CCC4=C(C3)C=C(C=N4)C(F)(F)F
Isomeric SMILES:CC(C)[C@@]1(CC[C@H](C1)[NH2+][C@H]2CCOC[C@H]2OC)C(=O)N3CCC4=C(C3)C=C(C=N4)C(F)(F)F
Uses MK-0812 is a potent C-C chemokine receptor type 2 (CCR2) antagonist.

Technology Process of [(3~{S},4~{S})-3-methoxyoxan-4-yl]-[(1~{R},3~{S})-3-propan-2-yl-3-[[3-(trifluoromethyl)-7,8-dihydro-5~{H}-1,6-naphthyridin-6-yl]carbonyl]cyclopentyl]azanium

There total 3 articles about [(3~{S},4~{S})-3-methoxyoxan-4-yl]-[(1~{R},3~{S})-3-propan-2-yl-3-[[3-(trifluoromethyl)-7,8-dihydro-5~{H}-1,6-naphthyridin-6-yl]carbonyl]cyclopentyl]azanium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%