8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE

Base Information Edit

Chemical Name:8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE
CAS No.:423165-13-3
Molecular Formula:C20H28N4
Molecular Weight:324.469
Hs Code.:2933990090
Mol file:423165-13-3.mol

Synonyms:8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE;8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane;8-Azabicyclo[3,2,1]octane3-[3-methyl-5-(1-methlethyl)-4H-1,2,4-triazol-4-yl]-8-(phenylmethyl);exo-8-Benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane;3-[3-Methyl-5-(1-Methylethyl)-4H-1,2,4-triazol-4-yl]-8-(phenylMethyl)-(3-exo)-8-azabicyclo[3.2.1]octane;Maraviroc interMediate(Tropine aMine );8-Azabicyclo[3.2.1]octane,3-[3-Methyl-5-(1-Methylethyl)-4H-1,2,4-triazol-4-yl]-8-(phenylMethyl)-,(3-exo)-;(1R,3s,5S)-8-Benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane

Suppliers and Price of 8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-Benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-exo-8-azabicyclo[3.2.1]octane
10mg
$ 145.00

Crysdot
(1R,3s,5S)-8-Benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 95+%
250mg
$ 320.00

Crysdot
(1R,3s,5S)-8-Benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 95+%
1g
$ 790.00

Chemenu
(1R,3s,5S)-8-Benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 95%
1g
$ 739.00

Biosynth Carbosynth
8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
250 mg
$ 100.00

Biosynth Carbosynth
8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
100 mg
$ 65.00

Biosynth Carbosynth
8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
1 g
$ 240.00

Biosynth Carbosynth
8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
500 mg
$ 160.00

Biosynth Carbosynth
8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
2 g
$ 350.00

American Custom Chemicals Corporation
EXO-8-BENZYL-3-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE 95.00%
5MG
$ 503.23

Total 56 raw suppliers

Chemical Property of 8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:149 ºC
Refractive Index:1.649
Boiling Point:481.467 °C at 760 mmHg
PKA:9.71±0.40(Predicted)
Flash Point:244.982 °C
PSA：33.95000
Density:1.207 g/cm³
LogP:4.01590
Storage Temp.:2-8°C

Purity/Quality:

99.9% ^*data from raw suppliers

8-Benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-exo-8-azabicyclo[3.2.1]octane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE

There total 15 articles about 8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 376348-67-3
exo-N-(8-benzyl-8-azabicyclo[3.2.1]oct-3-yl)-2-methylpropanamide

: 1068-57-1
acetic acid hydrazide

: 423165-13-3
exo-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane

Guidance literature:: exo-N-(8-benzyl-8-azabicyclo[3.2.1]oct-3-yl)-2-methylpropanamide; With pyridine; phosphorus pentachloride; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere; Cooling with ice;

acetic acid hydrazide; In tert-Amyl alcohol; at 0 - 20 ℃; for 17.5h; Inert atmosphere;

With acetic acid; In toluene; for 2h; Inert atmosphere; Reflux;
DOI:10.1021/acs.orglett.8b02087

Reference yield: 73.0%

: 376348-67-3
exo-N-(8-benzyl-8-azabicyclo[3.2.1]oct-3-yl)-2-methylpropanamide

: 6292-65-5
oxalic acid monohydrazide

: 423165-13-3
exo-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane

Guidance literature:: exo-N-(8-benzyl-8-azabicyclo[3.2.1]oct-3-yl)-2-methylpropanamide; With phosphorus pentachloride; In dichloromethane; at -5 - 20 ℃; for 4h; Inert atmosphere;

oxalic acid monohydrazide; In tert-Amyl alcohol; acetonitrile; at 10 - 20 ℃; for 15.5h; Inert atmosphere;

With oxalic acid monohydrazide; In tert-Amyl alcohol; acetonitrile; at 80 ℃; for 2h; Inert atmosphere;
DOI:10.1021/op8000614