5-(4-Aminophenyl)-2,4-pyrimidinediamine

Base Information

• Chemical Name: 5-(4-Aminophenyl)-2,4-pyrimidinediamine
• CAS No.: 71552-29-9
• Molecular Formula: C₁₀H₁₁N₅
• Molecular Weight: 201.231
• Mol file: 71552-29-9.mol

Synonyms:5-(4-amino-phenyl)-pyrimidine-2,4-diyldiamine;5-(4-Amino-phenyl)-pyrimidin-2,4-diyldiamin;2,4-Diamino-5-[p-aminophenyl]pyrimidine;5-(4-Aminophenyl)-2,4-pyrimidinediamine;

Chemical Property of 5-(4-Aminophenyl)-2,4-pyrimidinediamine

Chemical Property:

• Melting Point: 233 °C
• Boiling Point: 507.4 °C at 760 mmHg
• Flash Point: 293.2 °C
• PSA: 103.84000
• Density: 1.359 g/cm³
• LogP: 2.63380

Purity/Quality:

98%min ^*data from raw suppliers

5-(4-Aminophenyl)-2,4-pyrimidinediamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-(4-Aminophenyl)-2,4-pyrimidinediamine

There total 3 articles about 5-(4-Aminophenyl)-2,4-pyrimidinediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(4-nitro-phenyl)-pyrimidine-2,4-diyldiamine (873375-81-6) → 5-(4-amino-phenyl)-pyrimidine-2,4-diyldiamine (71552-29-9)

Guidance literature:

With ethanol; water; platinum; Hydrogenation_.Reagens 4: HCl;

DOI:10.1021/ja01152a060

Reference yield:

2,4-diamino-5-phenyl pyrimidine (18588-49-3) → 5-(4-amino-phenyl)-pyrimidine-2,4-diyldiamine (71552-29-9)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄; KNO₃

2: platinum; water; ethanol / Hydrogenation_.Reagens 4: HCl

With ethanol; sulfuric acid; water; potassium nitrate; platinum;

DOI:10.1021/ja01152a060

Reference yield:

phenyl(formyl)acetonitrile (5841-70-3) → 5-(4-amino-phenyl)-pyrimidine-2,4-diyldiamine (71552-29-9)

Guidance literature:

Multi-step reaction with 3 steps

1: diethyl ether / anschliessenden Erwaermen mit Guanidin in Aethanol

2: H₂SO₄; KNO₃

3: platinum; water; ethanol / Hydrogenation_.Reagens 4: HCl

With diethyl ether; ethanol; sulfuric acid; water; potassium nitrate; platinum;

DOI:10.1021/ja01152a060

upstream raw materials:

5-(4-nitro-phenyl)-pyrimidine-2,4-diyldiamine

2,4-diamino-5-phenyl pyrimidine

phenyl(formyl)acetonitrile